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Merck
모든 사진(3)

Key Documents

PLA0205

Sigma-Aldrich

Rabbit anti-CREB Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

동의어(들):

5′-monophosphate response element-binding protein CREB, CREB, CREB-1, active transcription factor CREB, cAMP-response element-binding protein-1, cAMP-responsive element-binding protein 1, cyclic adenosine 3′, transactivator protein

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모든 사진(3)

About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

100

항체 형태

affinity purified immunoglobulin

항체 생산 유형

primary antibodies

Grade

Powered by Bethyl Laboratories, Inc.

종 반응성

mouse, human

기술

immunohistochemistry: 1:100- 1:1,000
immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:2,000- 1:10,000

수납 번호(accession number)

NP_604391.1

배송 상태

wet ice

저장 온도

2-8°C

타겟 번역 후 변형

unmodified

유전자 정보

rabbit ... CREB(1385)

면역원

The epitope recognized by PLA0205 maps to a region between residue 250 and 300 of human cAMP responsive element binding protein 1 using the numbering given in entry NP_604391.1 (GeneID 1385).

물리적 형태

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

기타 정보

CREB (cyclic AMP response element-binding protein) is a ubiquitously expressed transcription factor that binds cAMP response elements to regulate gene transcription for various cellular responses such as glucose homeostasis, growth-factor dependent survival, and proliferation. CREB is also implicated to play a role in memory and mood.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Celine I Maeder et al.
Cell, 174(6), 1436-1449 (2018-08-28)
Synaptic vesicle and active zone proteins are required for synaptogenesis. The molecular mechanisms for coordinated synthesis of these proteins are not understood. Using forward genetic screens, we identified the conserved THO nuclear export complex (THOC) as an important regulator of
Zhenglin Zhao et al.
Neuroscience letters, 567, 19-23 (2014-03-29)
The role of neuropeptide Y (NPY) in the central nucleus of amygdala (CeA) in the preventive effects of acupuncture against ethanol withdrawal-induced anxiety was investigated. Rats were treated with 3g/kg/day of ethanol for 28 days, followed by 3 days of
Shuichi Moriya et al.
Journal of cellular biochemistry, 116(1), 142-148 (2014-08-29)
As the aged population is soaring, prevalence of osteoporosis is increasing. However, the molecular basis underlying the regulation of bone mass is still incompletely understood. Sympathetic tone acts via beta2 adrenergic receptors in bone and regulates the mass of bone
Catherine M Westbom et al.
The American journal of pathology, 184(10), 2816-2827 (2014-08-12)
Malignant mesothelioma (MM) is an aggressive tumor with no treatment regimen. Previously we have demonstrated that cyclic AMP response element binding protein (CREB) is constitutively activated in MM tumor cells and tissues and plays an important role in MM pathogenesis.
Sun-Young Lee et al.
International journal of oncology, 45(2), 675-682 (2014-05-29)
Nutlin-3 which occupies the p53 binding pocket in HDM2, has been reported to activate apoptosis through both the transcriptional activity-dependent and -independent programs of p53. Transcription-independent apoptosis by nutlin-3 is triggered by p53 which is translocated to mitochondria. However, we
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