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Merck
모든 사진(2)

Key Documents

PLA0097

Sigma-Aldrich

Rabbit anti-CBP Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

동의어(들):

CBP, KAT3A, RSTS, RTS, Rubinstein-Taybi syndrome

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

affinity purified immunoglobulin

항체 생산 유형

primary antibodies

Grade

Powered by Bethyl Laboratories, Inc.

종 반응성

human

농도

1 mg/mL

기술

immunoprecipitation (IP): 1-4 μg/mg
western blot: 1:1,000- 1:25,000

수납 번호(accession number)

NP_004371.1

배송 상태

wet ice

저장 온도

2-8°C

유전자 정보

rabbit ... CBP(1387)

면역원

The epitope recognized by PLA0097 maps to a region between residues 975 and 1025 of human CREB Binding Protein using the numbering given in entry NP_004371.1 (GeneID 1387).

물리적 형태

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

기타 정보

CBP [cAMP response element-binding protein (CREB)-binding protein] interacts with and is a transcriptional co-activator of a multitude of transcriptional regulators that includes CREB. CBP is structurally and functionally similar to p300 but is encoded by an independent gene. CBP coactivation may be achieved through the regulation of chromatin structure due to its ability to catalyze the acetylation of histones. CBP has potential tumor suppressor properties and is important to integrating cell-signaling cues for proliferation, differentiation and apoptosis.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

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Yujie Liu et al.
Molecular and cellular biology, 34(21), 3993-4007 (2014-08-27)
T-regulatory (Treg) cells are important to immune homeostasis, and Treg cell deficiency or dysfunction leads to autoimmune disease. A histone/protein acetyltransferase (HAT), p300, was recently found to be important for Treg function and stability, but further insights into the mechanisms

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