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PENNA

Penicillin G sodium salt

Name: Penicillin G sodium salt
Brand: SIGMA

~1650 U/mg

동의어(들):

Benzylpenicillin sodium salt

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About This Item

실험식(Hill 표기법):

C₁₆H₁₇N₂NaO₄S

CAS Number:

69-57-8

Molecular Weight:

356.37

Beilstein:

3834217

EC Number:

200-710-2

MDL number:

MFCD00069666

UNSPSC 코드:

51283424

PubChem Substance ID:

24899068

NACRES:

NA.85

양식

powder

Quality Level

200

특이 활성도

~1650 U/mg

solubility

H₂O: 100 mg/mL

항생제 활성 스펙트럼

Gram-negative bacteria
Gram-positive bacteria

동작 모드

cell wall synthesis | interferes

저장 온도

2-8°C

SMILES string

[Na+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O

InChI

1S/C16H18N2O4S.Na/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1

InChI key

FCPVYOBCFFNJFS-LQDWTQKMSA-M

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일반 설명

Penicillin G is a narrow spectrum antibiotic. It is effective against Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. Penicillin G contains β-lactam ring in their chemical structure.

애플리케이션

Penicillin G sodium salt has been used:

to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility
in cell culture alone as well as in combination with streptomycin and other antibiotics
to inhibit the synthesis of bacterial cell walls by inhibition of the cell wall peptidoglycan chain cross-lining

생화학적/생리학적 작용

Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking.

Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.

포장

1mu,10mu,100mu

주의사항

Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The sodium salt is soluble in H₂O at 100 mg/mL.