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Merck
모든 사진(1)

주요 문서

P3111

Sigma-Aldrich

Protease from Bacillus sp.

liquid, ≥16 U/g

동의어(들):

Savinase® 16.0L

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About This Item

EC Number:
MDL number:
UNSPSC 코드:
12352204
NACRES:
NA.54

생물학적 소스

Bacillus sp.

Quality Level

형태

liquid

특이 활성도

≥16 U/g

분자량

20-30 kDa

저장 온도

2-8°C

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애플리케이션

Protease is an enzyme used to break down proteins by hydrolyzing peptide bonds. Product P3111 is secreted from Bacillus sp.. It is a serine-type protease characterized by excellent performance at elevated temperature and pH. Product P3111 is extremely stable under harsh storage conditions, such as in the presence of sodium hypochlorite. Protease is used to degrade proteins, to study protease inhibitors and to study thermal inactivation kinetics.

생화학적/생리학적 작용

Protease catabolizes proteins by hydrolysis of peptide bonds. Proteases are inactivated by serine active-site inhibitors, such as phenylmethylsulfonyl fluoride (PMSF) and diisopropylfluorophosphate. Proteases, secreted from Bacillus sp., typically have molecular weights ranging from 20,000 to 30,000. They are typically stabilized by Ca2+ and have high isoelectric points. It is highly soluble in detergents at a wide range of pH and temperatures.

법적 정보

A product of Novozyme Corp.
Savinase is a registered trademark of Novozymes Corp.

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

개인 보호 장비

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

Yoshifumi Shimada et al.
Human pathology, 66, 1-9 (2017-02-27)
HER2-targeted therapy is considered effective for KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (CRC). In general, HER2 status is determined by the use of immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). Comprehensive genomic sequencing (CGS) enables the detection
Alessio Gomiero et al.
Environmental science and pollution research international, 26(24), 24407-24416 (2019-06-24)
In recent years, the occurrence of microplastics in the aquatic environment has gathered increasing scientific interest. Several studies have shown that the ingestion of microplastics may negatively influence the physiology of marine organisms having different feeding strategies, particularly in those
Juliana A S Leite et al.
Frontiers in nutrition, 8, 626475-626475 (2021-03-30)
Proteases present in milk are heat-sensitive, and their activities increase or decrease depending on the intensity of the thermal treatment applied. The thermal effects on the protease activity are well-known for bovine milk but poorly understood for ovine and caprine
Vikram Babu Kasaragod et al.
Neuron, 101(4), 673-689 (2019-02-02)
The frontline anti-malarial drug artemisinin and its derivatives have also been implicated in modulating multiple mammalian cellular pathways, including the recent identification of targeting γ-aminobutyric acid type A receptor (GABAAR) signaling in the pancreas. Their molecular mechanism of action, however
R Jha et al.
Journal of animal science, 93(3), 1039-1051 (2015-05-29)
Effects of treating corn and wheat distillers dried grains with solubles (DDGS) with a multicarbohydrase alone or in combination with a protease on porcine in vitro fermentation characteristics and the matrix structure of the DGGS before and after the fermentation

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