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Merck
모든 사진(1)

주요 문서

P2906

Sigma-Aldrich

Poly(ethylene glycol)

Hybri-Max, mol wt 3,000-3,700, waxy solid, BioReagent, suitable for hybridoma

동의어(들):

Polyethylene glycol, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
MDL number:
UNSPSC 코드:
12161902
PubChem Substance ID:
NACRES:
NA.75

생물학적 소스

synthetic (organic)

Quality Level

Grade

Hybri-Max

무균

autoclaved

제품 라인

BioReagent

양식

waxy solid

분자량

3,000-3,700

기술

cell culture | hybridoma: suitable

불순물

endotoxin, tested

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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일반 설명

Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It either exists in the form of a linear or branched structure. It aids in the purification and crystal growth of proteins and nucleic acids. PEG along with dextran is used to achieve an aqueous polymer two-phase system, which is essential for the purification of biological materials. It permits cell fusion through its interaction with the cell membrane.

애플리케이션

Poly(ethylene glycol) has been used in the production of monoclonal antibodies.
Recommended for cell fusion.

법적 정보

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

281.5 °F - closed cup

Flash Point (°C)

138.6 °C - closed cup

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Extensive nuclear localization of alpha-synuclein in normal rat brain neurons revealed by a novel monoclonal antibody
Yu S, et al.
Neuroscience journal, 145(2), 539-555 (2007)
Harris JM
Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications (2013)
Agathe Dubuisson et al.
Cell death & disease, 10(2), 101-101 (2019-02-06)
Development of therapeutic antibodies in oncology has attracted much interest in the past decades. More than 30 of them have been approved and are being used to treat patients suffering from cancer. Despite encouraging results, and albeit most clinical trials
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide

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