P0424

Prostaglandin F_2α tris salt

≥99%, synthetic, powder

• 동의어(들): (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dienoic acid tris salt, PGF_2α−Tris
• 실험식(Hill 표기법): C₂₀H₃₄O₅ · C₄H₁₁NO₃
• CAS Number: 38562-01-5
• Molecular Weight: 475.62
• Beilstein: 4087514
• EC Number: 254-002-3
• MDL number: MFCD00077863
• UNSPSC 코드: 12352401
• eCl@ss: 42020658
• PubChem Substance ID: 24898103
• NACRES: NA.77

속성

• 생물학적 소스: synthetic
• 분석: ≥99%
• 형태: powder
• 색상: white
• solubility: H₂O: 1 mg/mL; ethanol: 50 mg/mL
• 작용기: carboxylic acid; hydroxyl
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: NC(CO)(CO)CO.[H][C@]1(C\C=C/CCCC(O)=O)[C@@H](O)C[C@@H](O)[C@]1([H])\C=C\[C@@H](O)CCCCC
• InChI: 1S/C20H34O5.C4H11NO3/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25;5-4(1-6,2-7)3-8/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25);6-8H,1-3,5H2/b7-4-,13-12+;/t15-,16+,17+,18-,19+;/m0./s1
• InChI key: IYGXEHDCSOYNKY-RZHHZEQLSA-N
• 유전자 정보: human ... PTGFR(5737)

설명

일반 설명

Aqueous solutions are stable for 30 days at 2-8°C and for several months frozen at −0°C in single use aliquots. Avoid repeated freeze/thaw cycles.

생화학적/생리학적 작용

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. A positive feedback loop between endometrial PG F_2α and luteal oxytocin is responsible for completion of luteolysis.

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. Also stimulates contraction of smooth muscle, such as in bronchi, with possible involvement in asthma. This effect is at least partially mediated through tachykinin release.

안전성 정보

• 픽토그램: GHS08,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H302,H360FD
• 예방조치 성명서: P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 1B
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 개인 보호 장비: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges