O0877

Oxolinic acid

quinolone antibiotic

• 동의어(들): 5,8-Dihydro-5-ethyl-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid
• 실험식(Hill 표기법): C₁₃H₁₁NO₅
• CAS Number: 14698-29-4
• Molecular Weight: 261.23
• Beilstein: 620635
• EC Number: 238-750-8
• MDL number: MFCD00056775
• UNSPSC 코드: 51282935
• PubChem Substance ID: 24278604
• NACRES: NA.85

속성

• Quality Level: 200
• solubility: 0.5 M NaOH: soluble 50 mg/mL
• 항생제 활성 스펙트럼: Gram-negative bacteria
• 동작 모드: DNA synthesis | interferes; enzyme | inhibits
• 저장 온도: 2-8°C
• SMILES string: CCN1C=C(C(O)=O)C(=O)c2cc3OCOc3cc12
• InChI: 1S/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17)
• InChI key: KYGZCKSPAKDVKC-UHFFFAOYSA-N

설명

일반 설명

Chemical structure: quinolone

애플리케이션

Oxolinic acid is used to study new transmissible resistance mechanisms qnrA, qnrB, qnrS, and aac(6′)Ib-cr, in Escherichia coli and Salmonella enterica. Oxolinic acid is added to culture medium for the isolation of Gardnerella vaginalis.

생화학적/생리학적 작용

Oxolinic acid is a quinolone antibiotic. It is a DNA-gyrase (topoisomerase II) inhibitor used for studies on DNA winding and coiling and acts as a dopamine reuptake inhibitor for studies on dopaminergic neurotransmission processes.

기타 정보

5g,25g

Keep container tightly closed in a dry and well-ventilated place.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves