추천 제품
생물학적 소스
mouse
Quality Level
결합
unconjugated
항체 형태
ascites fluid
항체 생산 유형
primary antibodies
클론
NB2, monoclonal
분자량
antigen 500 kDa
포함
15 mM sodium azide
종 반응성
vertebrates, chicken
기술
indirect immunofluorescence: 1:400 using frozen sections of animal skeletal muscle
western blot: suitable
동형
IgG1
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
chicken ... NEB(101748402)
일반 설명
Nebulin is a 700kDa protein which is expressed in skeletal muscles. It possesses 35 amino acid repeats and a C terminal serine-rich and SH3 domains.
Nebulin is also localized to cardiac muscle. Monoclonal Anti-Nebulin (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.
특이성
Localizes nebulin in skeletal muscle of a wide variety of species from cold-blooded vertebrates to man. Does not crossreact with smooth or cardiac muscle, non-muscle tissue and cultured cells. Localizes nebulin within the I band of skeletal muscle sections by indirect immunofluorescence.
면역원
chicken breast nebulin.
애플리케이션
Monoclonal Anti-Nebulin antibody produced in mouse has been used in:
- immunohistochemistry
- fluorescent immunostaining
- western blotting
생화학적/생리학적 작용
Nebulin associates with the Z-line and thin actin filament in a sarcomere. It may function as a regulator of sarcomere thin filament length. The protein also acts as a structural link between sarcomeres. Nebulin interacts with the capping protein CapZ and has a role in controlling the localization of actin filaments.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
A 7.5-kb 3'-Terminal cDNA Sequence of Chicken Skeletal Muscle Nebulin Reveals Its Actin Binding Regions.
Suzuki T
Zoological Science (2000)
Identification of chicken nebulin isoforms of the 31-residue motifs and non-muscle nebulin.
Joo YM
Biochemical and Biophysical Research Communications (2004)
James D Morton et al.
Meat science, 143, 129-136 (2018-05-12)
High pressure processing (HPP) of pre-rigor longissimus thoracis (strip loin) from prime and bull animals substantially decreased the shear force and improved consumer eating attributes of the final meat product. The improved tenderness in both prime and bull meat was
Clinical phenotype, muscle MRI and muscle pathology of LGMD1F
Peterle E, et al.
Journal of Neurology, 260(8), 2033-2041 (2013)
Clinical phenotype, muscle MRI and muscle pathology
of LGMD1F
of LGMD1F
Enrico Peterle
Journal of Neurology (2013)
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