추천 제품
SMILES string
Br.COc1ccccc1N2CCN(CCCCN3C(=O)c4ccccc4C3=O)CC2
InChI
1S/C23H27N3O3.BrH/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28;/h2-5,8-11H,6-7,12-17H2,1H3;1H
InChI key
AXRUEPFPTQYHQD-UHFFFAOYSA-N
유전자 정보
human ... HTR1A(3350)
생화학적/생리학적 작용
Potent 5-HT1A serotonin receptor antagonist active in the nM range.
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
R L Dennis et al.
Poultry science, 91(4), 817-822 (2012-03-09)
Aggression and cannibalism in laying hens can differ in intensity and degree due to many factors, including genetics. Previous behavioral analysis of 2 strains of White Leghorns, DeKalb XL (DXL) and HGPS (a group-selected line for high group productivity and
Jaime Pei Pei Foong et al.
Neuroreport, 20(3), 325-330 (2009-02-05)
Serotonin (5-HT) plays a significant role in the regulation of intestinal secretion of water and electrolytes. The initial aim of this study was to use intracellular recording and specific antagonists to identify roles of 5-HT1A and 5-HT7 receptors of submucosal
E J Kessler et al.
Neuroscience, 154(4), 1187-1194 (2008-06-10)
Health problems can arise from de-synchrony between the external environment and the endogenous circadian rhythm, yet the circadian system is not able to quickly adjust to large, abrupt changes in the external daily cycle. In this study, we investigated the
L Rydelek-Fitzgerald et al.
Brain research, 532(1-2), 191-196 (1990-11-05)
NAN-190 has been reported to be a 5-HT1A antagonist in drug discrimination studies. In order to determine if the effect of NAN-190 was directly due to competitive inhibition at 5-HT1A receptors, 5-HT1A-mediated inhibition of adenylyl cyclase in hippocampal membranes was
James Oluwagbamigbe Fajemiroye et al.
Journal of ethnopharmacology, 141(3), 872-877 (2012-04-05)
Medicinal applications of Pimenta pseudocaryophyllus infusion as a diuretic and aphrodisiac agent as well as tranquilizer in the form of tea for the treatment of emotional tension in Brazilian folk medicine has been in practice since time immemorial. Despite its
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