N1638

Nystatin Suspension

suspension, non-animal origin, suitable for cell culture, BioReagent

• 동의어(들): Fungicidin, Mycostatin
• CAS Number: 1400-61-9
• UNSPSC 코드: 12352207
• PubChem Substance ID: 24897511
• NACRES: NA.76

속성

• product name: Nystatin Suspension, suspension, 10,000 unit/mL in DPBS, BioReagent, suitable for cell culture
• 제품 라인: BioReagent
• Quality Level: 200
• 형태: suspension
• 농도: 10,000 unit/mL in DPBS
• 기술: cell culture | mammalian: suitable
• 불순물: endotoxin, tested
• 색상: yellow
• 항생제 활성 스펙트럼: fungi; yeast
• 동작 모드: cell membrane | interferes
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: C[C@@H]1OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@]2(O)C[C@H](O)[C@H]([C@H](C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\C=C\C=C\C=C\C=C\CC\C=C\C=C\[C@H](C)[C@@H](O)[C@@H]1C)O2)C(O)=O
• InChI: 1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-36(53)35(52)20-19-31(49)21-32(50)22-33(51)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28+,29-,30+,31+,32+,33+,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1
• InChI key: VQOXZBDYSJBXMA-QEKUPDCNSA-N

설명

일반 설명

Chemical structure: polyene

애플리케이션

Nystatin suspension has been used:

• to inhibit caveolin-mediated endocytosis
• as a component of Eagle′s minimum essential medium (EMEM)
• to enumerate lactic acid bacteria (LAB)
• in preventing cell culture contamination and inducing interleukin (IL)-1, IL-8, and tumor necrosis factor a secretion in toll-like receptor 2 (TLR2)-expressing THP1 cells.

This product is recommended for use in cell culture applications at 24 mL/L.

생화학적/생리학적 작용

Nystatin is a polyene, broad-spectrum antibiotic, which modifies the microstructure of lipid rafts. It can sequester cholesterol present on the cell membrane of eukaryotes. Nystatin regulates immune responses through cytokine signaling, lymphocyte activation and pathogen recognition.

주의사항

This product is stable at 37°C for three days.

제조 메모

It is 0.1μ filtered and cell culture tested.

기타 정보

Nystatin suspension available in 20 mL and 100 mL pack size.
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable