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Merck
모든 사진(1)

Key Documents

N1016

Sigma-Aldrich

Nimesulide

동의어(들):

N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide

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About This Item

실험식(Hill 표기법):
C13H12N2O5S
CAS Number:
Molecular Weight:
308.31
EC Number:
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77

생물학적 소스

synthetic (organic)

Quality Level

분석

≥98% (TLC)

형태

powder

solubility

ethanol: 50 mg/mL

저장 온도

2-8°C

SMILES string

CS(NC1=C(OC2=CC=CC=C2)C=C([N+]([O-])=O)C=C1)(=O)=O

InChI

1S/C13H12N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h2-9,14H,1H3

InChI key

HYWYRSMBCFDLJT-UHFFFAOYSA-N

유전자 정보

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Nimesulide, a nonsteroidal anti-inflammatory drug (NSAID) belongs to the sulfonanilide class.

애플리케이션

Nimesulide has been used as a component in the reaction mixture to determine the activity of cyclooxygenase (COX) in spleen of chickens.

생화학적/생리학적 작용

Nimesulide can be used as a substitute to other nonsteroidal anti-inflammatory drugs (NSAIDs) to treat pain and inflammation of osteoarthritis for a short period. It can perform anti-inflammatory, analgesic and antipyretic activities.
Highly selective cyclooxygenase-2 inhibitor.

픽토그램

Skull and crossbones

신호어

Danger

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Nimesulide
Davis R and Brogden R N
Drugs, 48(3), 431-454 (1994)
Effects of dietary fish oil on NF
Yang X, et al.
The Journal of animal ecology, 20(3), 206-223 (2011)
Renata P Raffin et al.
Journal of biomedical nanotechnology, 8(2), 309-315 (2012-04-21)
Lipid nanoparticles are drug delivery systems able to increase bioavailability of poorly soluble drugs. They can be prepared with different lipid materials, especially natural lipids. Shea butter is a natural lipid obtained from the Butyrospermum parkii seed and rich in
Yuan Yuan et al.
International journal of pharmaceutics, 430(1-2), 114-119 (2012-04-17)
Poloxamer 407 has excellent thermo-sensitive gelling properties. Nevertheless, these gels possess inadequate poor bioadhesiveness and high permeability to water, which limited its' application as a thermoresponsive matrix. The main aim of the present investigation was to develop thermosensitive and mucoadhesive
Brijesh Kumar Singh et al.
PloS one, 7(4), e34200-e34200 (2012-04-18)
Nimesulide, an anti-inflammatory and analgesic drug, is reported to cause severe hepatotoxicity. In this study, molecular mechanisms involved in deranged oxidant-antioxidant homeostasis and mitochondrial dysfunction during nimesulide-induced hepatotoxicity and its attenuation by plant derived terpenes, camphene and geraniol has been

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