추천 제품
Quality Level
양식
liquid
농도
10 ng/μL
기술
DNA extraction: suitable
DNA sequencing: suitable
PCR: suitable
배송 상태
ambient
저장 온도
−20°C
관련 카테고리
일반 설명
Standardization of sample analysis is currently needed in microbiome genomics research workflow. Lack of standardization can lead to biases and errors in common processes during sample preparation and analysis such as sample amplification, sequencing and bioinformatics analyses.1 Akkermansia muciniphila genomic DNA microbial standard can serve as standard for benchmarking the performance along the workflow of microbiomics or meta-genomics analyses and as a tool to increase reproducibility and allow comparison of results obtained by different labs.
Akkermansia muciniphila is a gram negative, anaerobic, non motile, non spore forming and oval shaped bacterium. A. muciniphila inhabits the gastrointestinal tracts of more than 90% of adults and constitutes 1 to 4% of the fecal microbiota.2 A. muciniphila level was suggested to be a biomarker for a healthy intestin. 3
A. muciniphila degrades mucus and utilizes it as a carbon/nitrogen source. Consequently, the host produces additional mucus while the bacterium produces oligosaccharides and Short Chain Fatty Acids (SCFAs) that can be utilized by the host and trigger the immune system. An additional protective effect of the SCFA is stimulation of mucus-associated microbiota growth, that serves as a barrier against penetration of pathogens to intestinal cells. 2,4
Read here how to use our standards to ensure data integrity for your microbiome research.
Akkermansia muciniphila is a gram negative, anaerobic, non motile, non spore forming and oval shaped bacterium. A. muciniphila inhabits the gastrointestinal tracts of more than 90% of adults and constitutes 1 to 4% of the fecal microbiota.2 A. muciniphila level was suggested to be a biomarker for a healthy intestin. 3
A. muciniphila degrades mucus and utilizes it as a carbon/nitrogen source. Consequently, the host produces additional mucus while the bacterium produces oligosaccharides and Short Chain Fatty Acids (SCFAs) that can be utilized by the host and trigger the immune system. An additional protective effect of the SCFA is stimulation of mucus-associated microbiota growth, that serves as a barrier against penetration of pathogens to intestinal cells. 2,4
Read here how to use our standards to ensure data integrity for your microbiome research.
애플리케이션
Suitable for Quantitative standard for PCR, Sequencing and NGS
특징 및 장점
- Individual microbial standard for microbiomics and meta-genomics workflow
- Suitable standard for PCR, sequencing and NGS
- Improve Bioinformatics analyses
- Increases reproducibility
- Compare results lab to lab
물리적 형태
Liquid - The genomic DNA is provided at ≥10 ng/μL concentration in TE buffer pH 8.0
기타 정보
It is recommended to avoid freeze thaw cycles of this product.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Clara Belzer et al.
The ISME journal, 6(8), 1449-1458 (2012-03-23)
The human intestinal tract is colonized by a myriad of microbes that have developed intimate interactions with the host. In healthy individuals, this complex ecosystem remains stable and resilient to stressors. There is significant attention on the understanding of the
Chin Wen Png et al.
The American journal of gastroenterology, 105(11), 2420-2428 (2010-07-22)
Mucosa-associated bacteria are increased in inflammatory bowel disease (IBD), which suggests the possibility of an increased source of digestible endogenous mucus substrate. We hypothesized that mucolytic bacteria are increased in IBD, providing increased substrate to sustain nonmucolytic mucosa-associated bacteria. Mucolytic
Muriel Derrien et al.
International journal of systematic and evolutionary microbiology, 54(Pt 5), 1469-1476 (2004-09-25)
The diversity of mucin-degrading bacteria in the human intestine was investigated by combining culture and 16S rRNA-dependent approaches. A dominant bacterium, strain MucT, was isolated by dilution to extinction of faeces in anaerobic medium containing gastric mucin as the sole
J Paul Brooks et al.
BMC microbiology, 15, 66-66 (2015-04-17)
Characterizing microbial communities via next-generation sequencing is subject to a number of pitfalls involving sample processing. The observed community composition can be a severe distortion of the quantities of bacteria actually present in the microbiome, hampering analysis and threatening the
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