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Merck
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Key Documents

M9019

Sigma-Aldrich

IgG3, Lambda from murine myeloma

clone Y5606, purified immunoglobulin, buffered aqueous solution

동의어(들):

Mouse IgG3-λ

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.46

생물학적 소스

mouse

결합

unconjugated

항체 형태

purified immunoglobulin

클론

Y5606, monoclonal

형태

buffered aqueous solution

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

IgG (Immunoglobulin G) are the most common Immunoglobulin′s isotype in blood, lymph, cerebrospinal and peritoneal fluids and serve as key players in the humoral immune response. IgG include four subclasses (IgG1, IgG2, IgG3, and IgG4), consist of a variable Fab fragment (which includes the antibody recognition site) and a conserved Fc fragment.

애플리케이션

IgG3, λ from murine myeloma is suitable as isotype control in immunohistochemistry of formalin-fixed, paraffin-embedded sections and in FACS.
IgG3, Lambda from murine myeloma antibody has been used in Fluorescent activated cell sorting (FACS).

생화학적/생리학적 작용

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

물리적 형태

Solution in 0.02 M Tris buffered saline, pH 8.0, containing 0.02% sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Nicholas R Forsyth et al.
Cloning and stem cells, 8(1), 16-23 (2006-03-31)
Human embryonic stem cells (hESC) have great potential in regenerative medicine, provided that culture systems are established that maintain genomic integrity. Here we describe a comparison of the effects of culture in either physiologic oxygen (2%) or room oxygen (21%)
Nurlaely Mida Rachmawati et al.
International immunology, 25(2), 117-128 (2012-10-19)
Stimulation of Toll-like receptor 4 (TLR4) induces not only innate but also adaptive immune responses, and has been suggested to exert adjuvant effects. Additional to such positive effects, pre-stimulation of TLR4 induces endotoxin tolerance where animals are unresponsive to subsequent
Tracy Goodpaster et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 56(4), 347-358 (2007-12-12)
Fibroblasts are critical for tissue homeostasis, and their inappropriate proliferation and activation can result in common and debilitating conditions including fibrosis and cancer. We currently have a poor understanding of the mechanisms that control the growth and activation of fibroblasts
Systematic analysis of ATG13 domain requirements for autophagy induction
Wallot-Hieke N, et al.
Autophagy, 14(5), 743-763 (2018)
Gestur Vidarsson et al.
Frontiers in immunology, 5, 520-520 (2014-11-05)
Of the five immunoglobulin isotypes, immunoglobulin G (IgG) is most abundant in human serum. The four subclasses, IgG1, IgG2, IgG3, and IgG4, which are highly conserved, differ in their constant region, particularly in their hinges and upper CH2 domains. These

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