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Merck
모든 사진(1)

Key Documents

M7659

Sigma-Aldrich

Myosin Heavy Chain from rabbit muscle

buffered aqueous glycerol solution

동의어(들):

ATPase inactive whole chain myosin

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About This Item

CAS Number:
MDL number:
UNSPSC 코드:
12352202
NACRES:
NA.32

생물학적 소스

rabbit muscle

Quality Level

형태

buffered aqueous glycerol solution

기술

electrophoresis: suitable

UniProt 수납 번호

외래 활성

ATPase Activity ≤0.01 units/mg protein

저장 온도

−20°C

유전자 정보

일반 설명

Myosin heavy chain (MHC) is a motor protein of muscle thick filaments. MHC regulates ultrastructural diversity of myofibrils.

애플리케이션

Myosin Heavy Chain from rabbit muscle has been used:
  • in SDS analysis of myosin heavy chain (MHC) composition and content
  • for microinjection into the outflow of heart (blood serum) and the cephalic cavities (embryonic cerebrospinal fluid) of chick embryo
  • as a muscle protein, to study the role of ascorbate as a facilitator of glycogen storage in muscles

생화학적/생리학적 작용

Molecular motor involved in the contraction of muscles.

물리적 형태

Solution in 50% glycerol containing 0.6 M KCl and 0.005 M potassium phosphate, pH 6.5

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

L Wells et al.
The EMBO journal, 15(17), 4454-4459 (1996-09-02)
Myosin heavy chain (MHC) is the motor protein of muscle thick filaments. Most organisms produce many muscle MHC isoforms with temporally and spatially regulated expression patterns. This suggests that isoforms of MHC have different characteristics necessary for defining specific muscle
Myosin heavy chain isoforms regulate muscle function but not myofibril assembly.
Wells L, et al.
The Embo Journal, 15(17), 4454-4459 (1996)
Morphological and biochemical alterations of skeletal muscles from the genetically obese (ob/ob) mouse
Kemp JG, et al.
International journal of obesity (2005), 33(8), 831-831 (2009)
I Morano
Journal of molecular medicine (Berlin, Germany), 77(7), 544-555 (1999-09-24)
Cardiac contraction is triggered by the cyclic interaction of the "molecular motor" protein myosin with the actin filament, consuming ATP as the energy source to produce tension or shortening. The myosin heavy chain (MHC) contains the actin- and ATP-binding sites
A blood-CSF barrier function controls embryonic CSF protein composition and homeostasis during early CNS development
Parvas M, et al.
Developmental Biology, 321(1), 51-63 (2008)

문서

Myosins are a family of ATP-dependent motor proteins. Myosin II is the major contractile protein involved in eukaryotic muscle contraction by “walking” along actin microfilaments of the sarcomere

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

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