추천 제품
생물학적 소스
mouse
Quality Level
결합
unconjugated
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
F12B, monoclonal
양식
buffered aqueous solution
분자량
antigen 34 kDa
종 반응성
mouse, rat, human
기술
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1-2 μg/mL using rhabdomyosarcoma tissue sections
immunoprecipitation (IP): 2 μg using 1 mg protein lysate
indirect ELISA: suitable
indirect immunofluorescence: suitable
western blot: 1 μg/mL
동형
IgG1
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... MYOG(4656)
mouse ... Myog(17928)
rat ... Myog(29148)
일반 설명
Myogenin belongs to the basic helix-loop-helix (bHLH) superfamily.
Myogenin is a transcription factor present in the nucleus. It possesses an amino-acid rich region and a helix-loop-helix structure. The gene encoding it is localized on human chromosome 1q31-41 and has three exons.
면역원
rat recombinant myogenin (amino acids 30-224).
애플리케이션
Monoclonal Anti-Myogenin antibody produced in mouse has been used in immunohistochemistry, immunofluorescence and western blotting.
생화학적/생리학적 작용
Myogenin acts as a biomarker in rhabdomyosarcoma (RMS). It has a role in developmental processes, such as hematopoiesis, neurogenesis, myogenesis, tumor cell invasion and metastasis.
Myogenin acts as a regulator during myoblast and skeletal muscle differentiation. It is considered as a definite marker for skeletal muscle differentiation.
물리적 형태
Solution in phosphate buffered saline containing 0.08% sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Dysregulated Myogenesis in Rhabdomyosarcoma
Current Topics in Developmental Biology, 126(9), 285-297 (2018)
H Shen et al.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 49(2), e5124-e5124 (2016-02-13)
This study evaluated the effect of muscle satellite cells (MSCs) overexpressing myogenin (MyoG) on denervated muscle atrophy. Rat MSCs were isolated and transfected with the MyoG-EGFP plasmid vector GV143. MyoG-transfected MSCs (MTMs) were transplanted into rat gastrocnemius muscles at 1
Neuraminidase-1 mediates skeletal muscle regeneration
de Carvalho Neves J, et al.
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 1852(9), 1755-1764 (2015)
A Pertille et al.
Brazilian journal of biology = Revista brasleira de biologia, 77(1), 83-91 (2016-07-08)
The aim of this study was to analyze muscle regeneration after cryoinjury in the tibialis anterior muscle of young rats that were malnourished and then recovered. Forty Wistar rats were divided into a nourished group that received a normal protein
Hideki Ohnota et al.
Biochemical and biophysical research communications, 528(2), 398-403 (2020-01-14)
We have established a novel, simple, and highly reproducible method to generate skeletal muscle cells from mouse skin. Small pieces of skin from the back of mice were cultured in extracellular material-coated dishes in typical culture medium for about 3
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