추천 제품
일반 설명
Research area: Cell Structure
Lipodisq® polymers contain styrene and maleic acid monomer units. This product is the pre-hydrolyzed form of the SMA polymer, with styrene and maleic acid monomers. These polymer-lipid complexes are mainly generated by detergent-free methods.
Functional pH range: 6.0 - 9.0
Lipodisq® polymers contain styrene and maleic acid monomer units. This product is the pre-hydrolyzed form of the SMA polymer, with styrene and maleic acid monomers. These polymer-lipid complexes are mainly generated by detergent-free methods.
Functional pH range: 6.0 - 9.0
애플리케이션
Lipodisq® reagents are novel polymers derived from styrene and maleic acid. Lipodisq polymers are capable of forming nanosized lipid-based discoidal particles capable of incorporating membrane proteins. The Lipodisq technology can solubilize commonly used lipids such as dimyristoylphosphatidylcholine (DMPC) without the use of detergents. In general, Lipodisq polymers are potentially useful in mitigating the use of detergents for the solubilization of membrane proteins. Lipodisqs typically have a diameter of 9-10 nm at pH 7.4.
법적 정보
Lipodisq is a registered trademark of Malvern Cosmeceutics Limited
관련 제품
제품 번호
설명
가격
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
이미 열람한 고객
Indra D Sahu et al.
Biochemistry, 52(38), 6627-6632 (2013-08-30)
Pulsed EPR DEER structural studies of membrane proteins in a lipid bilayer have often been hindered by difficulties in extracting accurate distances when compared to those of globular proteins. In this study, we employed a combination of three recently developed
Detergent-Free Formation and Physicochemical Characterization of Nanosized Lipid-Polymer Complexes: Lipodisq
Orwick MC, et al.
Angewandte Chemie (International ed. in English), 51(19), 4653-4657 (2012)
Juan F Bada Juarez et al.
Chemistry and physics of lipids, 222, 51-58 (2019-05-19)
Lipodisq™ nanoparticles have been used to extract surface lipids from the cuticle of two strains (wild type, N2 and the bacteria-resistant strain, agmo-1) of the C. elegans nematode without loss of viability. The extracted lipids were characterized by thin layer
Juan Francisco Bada Juarez et al.
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Maria Lyngaas Torgersen et al.
Journal of biomedical nanotechnology, 16(4), 419-431 (2020-09-25)
Many promising pharmaceutically active compounds have low solubility in aqueous environments and their encapsulation into efficient drug delivery vehicles is crucial to increase their bioavailability. Lipodisq nanoparticles are approximately 10 nm in diameter and consist of a circular phospholipid bilayer
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