L090000

Dichloromethane

• 동의어(들): Methylene chloride
• 실험식(Hill 표기법): CH₂Cl₂
• CAS Number: 75-09-2
• Molecular Weight: 84.93
• Beilstein: 1730800
• EC Number: 200-838-9
• MDL number: MFCD00000881
• UNSPSC 코드: 12352101
• PubChem Substance ID: 329817376
• NACRES: NA.21

속성

• vapor density: 2.9 (vs air)
• vapor pressure: 24.45 psi ( 55 °C); 6.83 psi ( 20 °C)
• 유형: for DNA synthesis
• 제품 라인: Proligo Reagents
• 형태: liquid
• autoignition temp.: 1223 °F
• 포함: amylene as stabilizer
• expl. lim.: 22 %
• 저장 조건: dry at room temperature
• 불순물: ≤50 ppm water content (Karl Fischer)
• 색상: clear
• refractive index: n/D 1.421-1.425; n20/D 1.424 (lit.)
• bp: 39.8-40 °C (lit.)
• mp: −95 °C (lit.)
• density: 1.325 g/mL at 25 °C (lit.)
• SMILES string: ClCCl
• InChI: 1S/CH2Cl2/c2-1-3/h1H2
• InChI key: YMWUJEATGCHHMB-UHFFFAOYSA-N

설명

일반 설명

In the solid-phase synthesis of oligonucleotides, liquid reagents are used in each step of the synthesis cycle. Overall synthesis performance, and therefore total product yield and purity of the crude oligonucleotide, is highly dependent on the chemical purity of the monomers and the supporting liquid reagents and other solvents like ethylacetate, dichloromethane, and dimethylformadine .Dichloromethane is an ordinary organic solvent frequently utilized in peptide synthesis. Under normal circumstances, DCM maintains highly stable and will not cause significant side reactions in peptide synthesis. It is a chlorinated organic solvent that is susceptible to degradation with time. This can be suppressed by adding amylene as a stabilizer.Dichloromethane has been tested as a solvent medium for the dipyridine-chromium(VI) oxide. Solubility was reported to be 12.5g/100ml. The role of the quantity of TiO2 loading on activated carbon support employed in the photodecomposition of dichloromethane has been investigated.

애플리케이션

Dichloromethane may be used as a solvent for the preparation of stock solutions of carotenoids. It may be employed as a solvent in the synthesis of polylactide-based (PLA) thin films. IT is also suitable as a solvent for the oxidation of primary and secondary alcohols using dipyridine-chromium(VI) oxide.

안전성 정보

• 픽토그램: GHS08,GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H336,H351
• 예방조치 성명서: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Central nervous system
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 2
• Flash Point (°F): does not flash
• Flash Point (°C): does not flash