I9910

Ibutilide hemifumarate salt

≥98% (HPLC)

• 동의어(들): (±)-N-[4-[4-(Ethylheptylamino)-1-hydroxybutyl]phenyl]-methanesulfonamide hemifumarate salt, Corvert
• 실험식(Hill 표기법): C₂₀H₃₆N₂O₃S · 0.5C₄H₄O₄
• CAS Number: 122647-32-9
• Molecular Weight: 442.61
• MDL number: MFCD01715410
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329815470
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 양식: solid
• 색상: off-white to tan
• solubility: H₂O: >20 mg/mL
• 저장 온도: room temp
• SMILES string: OC(=O)\C=C\C(O)=O.CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1.CCCCCCCN(CC)CCCC(O)c2ccc(NS(C)(=O)=O)cc2
• InChI: 1S/2C20H36N2O3S.C4H4O4/c2*1-4-6-7-8-9-16-22(5-2)17-10-11-20(23)18-12-14-19(15-13-18)21-26(3,24)25;5-3(6)1-2-4(7)8/h2*12-15,20-21,23H,4-11,16-17H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+
• InChI key: PCIOHQNIRPWFMV-WXXKFALUSA-N
• 유전자 정보: human ... KCNH2(3757)

설명

생화학적/생리학적 작용

Ibutilide hemifumarate salt is considered a new generation "pure" Class III antiarrhythmic agent.

Ibutilide hemifumarate salt is considered a new generation "pure" Class III antiarrhythmic agent. Ibutilide binds to and alters the activity of hERG potassium channels, delayed inward rectifier potassium (IKr) channels and L-type (dihydropyridine sensitive) calcium channels.

특징 및 장점

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS08,GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H361d
• 예방조치 성명서: P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable