콘텐츠로 건너뛰기
Merck
모든 사진(1)

Key Documents

View All Documentation

I1145

Sigma-Aldrich

Interleukin-5 from mouse

≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture

동의어(들):

IL-5

로그인조직 및 계약 가격 보기
모든 사진(1)

About This Item

MDL number:
MFCD00131402
UNSPSC 코드:
12352202
NACRES:
NA.32

생물학적 소스

mouse

Quality Level

200

재조합

expressed in baculovirus infected Sf21 cells

분석

≥97% (SDS-PAGE)

형태

lyophilized powder

효능

0.04-0.30 ng/mL EC50

분자량

45-50 kDa

포장

pkg of 5 μg

기술

cell culture | mammalian: suitable

불순물

endotoxin, tested

UniProt 수납 번호

P04401

저장 온도

−20°C

유전자 정보

mouse ... Il5(16191)

관련 카테고리

생화학적/생리학적 작용

Interleukin-5 exhibits activity on eosinophils, B cells, and thymocytes. Human and mouse IL-5 exhibit homology at the nucleotide and amino acid levels and show species cross-reactivity.
Interleukin-5 is a product of activated T lymphocytes and exhibits activity on eosinophils, B cells and thymocytes. Synonyms or biological activities attributed to IL-5 include: EDF (eosinophil differentiating factor), BCGF-II (B cell growth factor-II), TRF (T cell replacing factor), IgA-EF (IgA enhancing factor) and EO-CSF (eosinophil colony stimulating factor). Natural IL-5 is a 45-50 kDa dimeric glycoprotein, although glycosylation is not required for activity. Human and mouse IL-5 exhibit homology at the nucleotide and amino acid levels and show species cross-reactivity.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.25 mg bovine serum albumin.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Stefan Rebhandl et al.
European journal of immunology, 44(7), 2175-2187 (2014-03-29)
Activation-induced deaminase (AID) is a DNA-mutating enzyme that mediates class-switch recombination as well as somatic hypermutation of antibody genes in B cells. Due to off-target activity, AID is implicated in lymphoma development by introducing genome-wide DNA damage and initiating chromosomal
Yuan Wang et al.
Journal of immunology (Baltimore, Md. : 1950), 195(3), 1171-1181 (2015-06-28)
Complement is implicated in asthma pathogenesis, but its mechanism of action in this disease remains incompletely understood. In this study, we investigated the role of properdin (P), a positive alternative pathway complement regulator, in allergen-induced airway inflammation. Allergen challenge stimulated
Xiang Zhu et al.
American journal of physiology. Gastrointestinal and liver physiology, 306(11), G974-G982 (2014-04-20)
Extracellular acidification has been observed in allergic inflammatory diseases. Recently, we demonstrated that the proton-sensing receptor G protein-coupled receptor 65 (GPR65) regulates eosinophil survival in an acidic environment in vitro and eosinophil accumulation in an allergic lung inflammation model. For
Chisa Nakashima et al.
The Journal of allergy and clinical immunology, 134(1), 100-107 (2014-04-10)
Although eosinophils have been detected in several human skin diseases in the vicinity of basophils, how eosinophils infiltrate the skin and the role of eosinophils in the development of skin inflammation have yet to be examined. Using murine irritant contact

문서

Interleukin Family (IL)

The Interleukins comprise a disparate group of cytokines and growth factors that are produced by and released from leukocytes. Interleukin-1β (1L-1β) is released primarily from stimulated macrophages and monocytes and plays a key role in inflammatory and immune responses and may induce anti-tumor immunity.

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.