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Merck
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주요 문서

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I0909

Sigma-Aldrich

6-Iodonordihydrocapsaicin

≥98% (HPLC), solid

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모든 사진(2)

About This Item

실험식(Hill 표기법):
C17H26INO3
CAS Number:
859171-97-4
Molecular Weight:
419.30
MDL number:
MFCD09878233
UNSPSC 코드:
12352200
PubChem Substance ID:
24895913
NACRES:
NA.77

Quality Level

100

분석

≥98% (HPLC)

양식

solid

저장 조건

protect from light

색상

white

solubility

DMSO: ~44 mg/mL
H2O: insoluble

저장 온도

2-8°C

SMILES string

CCCCCCCCC(=O)NCc1cc(OC)c(O)cc1I

InChI

1S/C17H26INO3/c1-3-4-5-6-7-8-9-17(21)19-12-13-10-16(22-2)15(20)11-14(13)18/h10-11,20H,3-9,12H2,1-2H3,(H,19,21)

InChI key

AAORACFZMYMFCG-UHFFFAOYSA-N

유전자 정보

human ... TRPV1(7442)

생화학적/생리학적 작용

TRPV1 (V1) vanilloid receptor antagonist.

픽토그램

Exclamation mark
GHS07

신호어

Warning

유해 및 위험 성명서

H315 - H319 - H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
074K4604

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문서 라이브러리 방문

Giovanni Appendino et al.
British journal of pharmacology, 139(8), 1417-1424 (2003-08-19)
1. The C-5 halogenation of the vanillyl moiety of resiniferatoxin, an ultrapotent agonist of vanilloid TRPV1 receptors, results in a potent antagonist for these receptors. Here, we have synthesized a series of halogenated derivatives of 'synthetic capsaicin' (nonanoyl vanillamide=nordihydrocapsaicin) differing
Yuriko Oi-Kano et al.
The Journal of nutritional biochemistry, 40, 209-218 (2016-12-13)
Oleuropein is the pungent principle of raw olives. Oleuropein aglycone (OA) is a major phenolic compound in extra virgin olive oil and the absorbed form of oleuropein. We aimed to determine the mechanism underlying the nutritional effects of oleuropein and
Daniela L Uliana et al.
Journal of psychopharmacology (Oxford, England), 34(9), 1043-1055 (2020-07-09)
Blockade of cannabinoid CB1 or vanilloid TRPV1 receptors in the ventromedial prefrontal cortex of rats respectively increases or decreases the conditioned emotional response during re-exposure to a context previously paired with footshocks. Although these mechanisms are unknown, they may involve
Manoela V Fogaça et al.
Pharmacology, biochemistry, and behavior, 129, 7-13 (2014-12-03)
Hemopressin (PVNFKFLSH; HP) is an orally active peptide derived from rat hemoglobin α-chain that could act as an inverse agonist at cannabinoid type 1 receptors (CB1). Here, we aim to investigate possible behavioral effects of HP in male Wistar rats
Azucena Perez-Burgos et al.
The Journal of physiology, 593(17), 3943-3957 (2015-06-19)
Certain probiotic bacteria have been shown to reduce distension-dependent gut pain, but the mechanisms involved remain obscure. Live luminal Lactobacillus reuteri (DSM 17938) and its conditioned medium dose dependently reduced jejunal spinal nerve firing evoked by distension or capsaicin, and

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