I0654

Interleukin-1 Soluble Receptor, Type I human

>97% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

• 동의어(들): (IL-1 sRI)
• MDL number: MFCD01323730
• UNSPSC 코드: 51111800
• NACRES: NA.32

속성

• 생물학적 소스: human
• Quality Level: 100
• 재조합: expressed in NSO cells
• 분석: >97% (SDS-PAGE)
• 양식: lyophilized powder
• 분자량: 36 kDa
• 포장: pkg of 0.1 mg
• 불순물: endotoxin, tested
• UniProt 수납 번호: P14778
• 저장 온도: −20°C
• 유전자 정보: human ... IL1R1(3554)

설명

일반 설명

Interleukin-1 type 1 receptor (IL1R1) is a glycoprotein. It is mainly expressed on endothelial cells, epithelial cells, hepatocytes, fibroblasts, epidermal dendritic cells as well as T lymphocytes.

생화학적/생리학적 작용

Interleukin-1 (IL-1), a cytokine, is a key regulator of acute and chronic inflammation. The IL-1 associated responses are achieved by association of IL-1 with IL-1 type 1 receptor (IL1R1).

Recombinant human IL-1 soluble receptor I is a transmembrane protein and a member of the immunoglobulin superfamily. It is expressed predominantly by T cells, fibroblasts, and endothelial cells.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5.0 mg bovine serum albumin

분석 메모

The bioactivity is measured by its ability to inhibit the IL-1β-dependent proliferation of a murine helper T cell line, D10.G4.1.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable