추천 제품
product name
DL-β-Hydroxybutyric acid sodium salt, ~98%
분석
~98%
Quality Level
형태
powder
solubility
water: 1 g/10 mL, clear, colorless
저장 온도
2-8°C
SMILES string
[Na].CC(O)CC(O)=O
InChI
1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1
InChI key
NBPUSGBJDWCHKC-UHFFFAOYSA-M
애플리케이션
DL-β-Hydroxybutyric acid sodium salt has been used:
- as a standard for quantifying blood plasma and milk β-hydroxybutyric acid in Danish Jersey cows
- to investigate its anticonvulsant effects in epilepsy induced rats
- to induce hyperketonemia in Holstein dairy cows
생화학적/생리학적 작용
β-Hydroxybutyric acid is a ketone body present in the rumen epithelium of liver cells. Its interconversion to acetoacetate influences the acid-base balance and is coupled NADH generation from (nicotinamide adenine dinucleotide) NAD+, measured fluorimetrically. A high plasma level of β-hydroxybutyric acid is implicated in diabetic ketoacidosis. It traverses the blood-brain barrier as a monocarboxylic acid. β-Hydroxybutyric acid may play a protective role in dopaminergic neurodegeneration in Parkinson′s disease model. β-Hydroxybutyric acid is a ligand for G protein-coupled receptor(GPR109A) and favors inhibition of secretion, transcription and translation of growth hormone (GH) and prolactin (PRL) gene in cow anterior pituitary cells (DCAPCs).
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Influence of DL-beta-hydroxybutyric acid on cell proliferation and calcium influx
Cheng S, et al.
Biomacromolecules, 6(2), 593-597 (2005)
Fluorometric determination of beta-hydroxybutyrate in milk and blood plasma
Larsen T and Nielsen NI
Journal of Dairy Science, 88(6), 2004-2009 (2005)
Emily R Cope et al.
Physiological genomics, 50(6), 468-477 (2018-04-07)
To identify molecular pathways that couple metabolic imbalances and reproduction, we randomly assigned 10 castrated male sheep to be centrally injected into the lateral ventricle through intracerebroventricular cannulas with 1 ml of β-hydroxybutyric acid sodium salt solution (BHB; 12,800 µmol/l)
Jianping Si et al.
Experimental and therapeutic medicine, 14(1), 765-770 (2017-07-05)
The present study aimed to investigate the anticonvulsant effects of β-hydroxybutyrate (BHB) in a kainic acid (KA)-induced rat seizure model. The concentrations of BHB and glucose were detected in the blood prior to exogenous BHB administration. Three different doses of
M Lehmann et al.
Journal of dairy science, 96(2), 889-896 (2012-12-12)
During a mammary immune response, the integrity of the blood-milk barrier is negatively affected and becomes leaky. The aim of the present study was to demonstrate the blood origin, and to investigate changes in the concentration, of various constituents including
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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