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Merck
모든 사진(1)

Key Documents

H6291

Sigma-Aldrich

IL-1β human

HumanKine®, recombinant, Xeno-free, >95% (SDS-PAGE), suitable for cell culture

동의어(들):

IL-1β, Lymphocyte activating factor

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About This Item

MDL number:
UNSPSC 코드:
12352202
NACRES:
NA.77

product name

Interleukin-1β human, IL-1β, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture, endotoxin tested

생물학적 소스

human

Quality Level

재조합

expressed in HEK 293 cells

분석

≥95% (SDS-PAGE)

형태

lyophilized powder

효능

≤0.05 ng/mL EC50

품질

endotoxin tested

분자량

dimer 18-25 kDa (glycosylated)

포장

pkg of 10 μg

기술

cell culture | mammalian: suitable

불순물

<1 EU/μg

UniProt 수납 번호

저장 온도

−20°C

유전자 정보

human ... IL1B(3553)

유사한 제품을 찾으십니까? 방문 제품 비교 안내

생화학적/생리학적 작용

Interleukin-1 (IL-1), originally known as Lymphocyte Activating Factor (LAF), activates T cell lymphocytes, which then proliferate and secrete interleukin-2 (IL-2). IL-1 is released primarily from stimulated macrophages and monocytes, but has also been shown to be released from several other types and is thought to play a key role in inflammatory and immune responses. Other synonyms for IL-1 include: endogenous pyrogen (EP), mitogenic protein (MP), Helper Peak-1 (HP-1), T Cell Replacing Factor III (TRF III or TRFM), B Cell Activating Factor (BAF) and B Cell Differentiation Factor (BDF) The two closely related agents Interleukin-1α (IL-1α) and Interleukin-1β (IL-1β) share 62% homology in amino acid sequence and elicit nearly identical biological responses. IL-1α and IL-1β are both approximately 17 kDa with some heterogeneity in the amount of glycosylation.

물리적 형태

Lyophilized from a 0.2 μm filtered solution of 1x PBS.

제조 메모

HumanKine Recombinant Human IL-1β, expressed in human HEK 293 cells, is a glycosylated monomer with a molecular mass of 18-25 kDa. Production in human HEK 293 cells offers authentic glycosylation. Glycosylation contributes to stability in cell growth media and other applications.

분석 메모

The activity is determined by the dose-dependent stimulation of the proliferation of mouse D10S cells.

법적 정보

HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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