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F3886

Sigma-Aldrich

Fentanyl citrate salt

동의어(들):

N-Phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]propanamide citrate salt

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About This Item

실험식(Hill 표기법):
C22H28N2O · C6H8O7
CAS Number:
990-73-8
Molecular Weight:
528.59
EC Number:
213-588-0
MDL number:
MFCD00058359
UNSPSC 코드:
12352200
PubChem Substance ID:
329799707
NACRES:
NA.77

약물 제어

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

SMILES string

OC(=O)CC(O)(CC(O)=O)C(O)=O.CCC(=O)N(C1CCN(CC1)CCc2ccccc2)c3ccccc3

InChI

1S/C22H28N2O.C6H8O7/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-12,21H,2,13-18H2,1H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key

IVLVTNPOHDFFCJ-UHFFFAOYSA-N

유전자 정보

human ... OPRM1(4988)

유사한 제품을 찾으십니까? 방문 제품 비교 안내

생화학적/생리학적 작용

Phenylpiperidine analgesic that is 80 times more potent than morphine as an analgesic and 6000 times more potent than morphine as a μ opioid receptor agonist.

픽토그램

Skull and crossbones
GHS06

신호어

Danger

유해 및 위험 성명서

H300 + H310 + H330,H336

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - STOT SE 3

표적 기관

Central nervous system

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Willem M Otte et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 35(8), 1358-1367 (2015-05-15)
Hemispherectomy is often followed by remarkable recovery of cognitive and motor functions. This reflects plastic capacities of the remaining hemisphere, involving large-scale structural and functional adaptations. Better understanding of these adaptations may (1) provide new insights in the neuronal configuration
Anouk Wezel et al.
Atherosclerosis, 241(2), 289-296 (2015-06-13)
Activated mast cells have been identified in the intima and perivascular tissue of human atherosclerotic plaques. As mast cells have been described to release a number of chemokines that mediate leukocyte fluxes, we propose that activated mast cells may play
Jennifer D Zwicker et al.
Journal of applied physiology (Bethesda, Md. : 1985), 117(8), 857-868 (2014-08-12)
Opioids activate glia in the central nervous system in part by activating the toll-like receptor 4 (TLR4)/myeloid differentiation 2 (MD2) complex. TLR4/MD2-mediated activation of glia by opioids compromises their analgesic actions. Glial activation is also hypothesized as pivotal in opioid-mediated
Houssam G Kotrach et al.
Journal of applied physiology (Bethesda, Md. : 1985), 118(11), 1406-1414 (2015-06-03)
Few therapies exist for the relief of dyspnea in restrictive lung disorders. Accumulating evidence suggests that nebulized opioids selective for the mu-receptor subtype may relieve dyspnea by modulating intrapulmonary opioid receptor activity. Our respective primary and secondary objectives were to
Ariana M Nelson et al.
Anesthesiology, 111(6), 1327-1333 (2009-11-26)
Opioids disrupt sleep and adenosine promotes sleep, but no studies have characterized the effects of opioids on adenosine levels in brain regions known to regulate states of arousal. Delivering opioids to the pontine reticular formation (PRF) and substantia innominata (SI)
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