F0931

Factor Va human

≥1500 units/mg protein

• MDL number: MFCD01093755
• UNSPSC 코드: 12352202
• NACRES: NA.61

속성

• 생물학적 소스: human
• Quality Level: 200
• 양식: solution
• 특이 활성도: ≥1500 units/mg protein
• 분자량: 168 kDa
• 기술: ligand binding assay: suitable
• UniProt 수납 번호: P12259
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: human ... F5(2153)

설명

일반 설명

Factor V, a glycoprotein is usually seen in the alpha granules of platelets and in plasma.

Factor Va is the activated form of factor V and the cofactor of Xa. It is a component of the prothrombinase complex.

생화학적/생리학적 작용

Factor V is a key component in blood coagulation systems, where deficiencies can inhibit thrombin generation and affect hemostasis. It has been used in studies of coagulopathic bleeding which occurs following injury and is a leading cause of hospital deaths.

Factor Va serves as a receptor and positive effector of factor Xa. Hence it can efficiently help in the conversion of prothrombin to thrombin.

결합

View this factors role in the Coagulation Cascade

단위 정의

One unit is equivalent to the Factor V activity in 1.0 mL of normal human plasma at pH 7.4 at 37 °C.

물리적 형태

Aqueous solution containing 50% (v/v) glycerol and 5mM CaCl₂

면책조항

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable