추천 제품
생물학적 소스
mouse lung
Quality Level
형태
powder
UniProt 수납 번호
저장 온도
2-8°C
InChI
1S/C27H48N6O6/c1-9-17(6)23(32-24(36)19(13-15(2)3)30-18(7)34)26(38)29-14-21(35)31-22(16(4)5)27(39)33-12-10-11-20(33)25(37)28-8/h15-17,19-20,22-23H,9-14H2,1-8H3,(H,28,37)(H,29,38)(H,30,34)(H,31,35)(H,32,36)/t17-,19-,20-,22-,23-/m0/s1
InChI key
DPUYCSDGMSDKKV-MKBYFEBXSA-N
유전자 정보
mouse ... Eln(13717)
일반 설명
Elastin is a key protein of the extracellular matrix (ECM). It is made up of glycoproteins, glycosaminoglycans, collagen and proteoglycans. Elastin is mainly localized in the arteries and lungs.
Elastin is an important extracellular matrix (ECM) protein derived from its precursor tropoelastin. Elastin is highly flexible than collagen.
애플리케이션
Elastin mouse lung has been used as an extracellular matrix (ECM) protein for coating of plates.
생화학적/생리학적 작용
Elastin delivers elasticity to tissues and organs. In addition, it is also involved in paracrine signaling. Genetic variation in the gene coding for elastin causes Williams-Beuren syndrome, cutis laxa and supravalvular aortic stenosis (SVAS).
Elastin plays a critical role in alveolization in the fetal lung. In vivo radiochemical labelling indicates that mouse or rat lung elastin is synthesized primarily prenatally and during the first two weeks of life. It turns over very slowly, with a half-life estimated at several years.
Elastin plays an important role in the elasticity and resilience of many tissues, such as ligament, tendon and elastic cartilage. It is also involved in the elasticity of large arteries and skin.
제조 메모
Purified under mild extraction conditions to minimize peptide bond cleavage as described by Starcher, et al.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Yulian Wang et al.
Journal of visualized experiments : JoVE, (60) (2012-03-01)
Mechanical forces generated in utero by repetitive breathing-like movements and by fluid distension are critical for normal lung development. A key component of lung development is the differentiation of alveolar type II epithelial cells, the major source of pulmonary surfactant.
Karolina Chrabaszcz et al.
Cancers, 13(2) (2021-01-10)
The current understanding of mechanisms underlying the formation of metastatic tumors has required multi-parametric methods. The tissue micro-environment in secondary organs is not easily evaluated due to complex interpretation with existing tools. Here, we demonstrate the detection of structural modifications
Jiří Kanta
Frontiers in physiology, 7, 491-491 (2016-11-09)
A characteristic feature of liver cirrhosis is the accumulation of large amounts of connective tissue with the prevailing content of type I collagen. Elastin is a minor connective tissue component in normal liver but it is actively synthesized by hepatic
Elastin in the Liver
Kanta J.
Frontiers in Physiology, 7, 491-491 (2016)
An experimental system to study mechano transduction in fetal lung cells
Wang Y, et al.
Journal of Visualized Experiments, 7(60), e3543-e3543 (2012)
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