E1257

Epidermal Growth Factor from murine submaxillary gland

lyophilized powder, BioReagent, suitable for cell culture

• 동의어(들): EGF, Epidermal cell growth factor
• CAS Number: 62229-50-9
• EC Number: 263-468-7
• MDL number: MFCD01634807
• UNSPSC 코드: 12352202
• NACRES: NA.32

속성

• 생물학적 소스: mouse submaxillary glands
• Quality Level: 200
• 제품 라인: BioReagent
• 분석: ≥98% (SDS-PAGE)
• 형태: lyophilized powder
• 효능: 0.02-2.0 ng/mL EC₅₀
• 포장: pkg of 0.1 mg
• 저장 조건: avoid repeated freeze/thaw cycles
• 기술: cell culture | mammalian: suitable
• 불순물: endotoxin, tested
• 색상: white
• UniProt 수납 번호: P01132
• 저장 온도: 2-8°C
• 유전자 정보: mouse ... Egf(13645)

설명

일반 설명

Epidermal growth factor (EGF) is the member of EGF-like family of growth factors, that binds to EGF receptor. It is majorly expressed in kidney, parotid gland and salivary gland.

애플리케이션

Epidermal Growth Factor from murine submaxillary gland has been used

• in studying its effects on the development of caustic esophageal stricture in rats
• for preparation of MCF-10A cell line
• for the culture of primary hair follicle stem cells from arbas cashmere goat (gHFSCs) and adhesion of hair follicles (HF)

생화학적/생리학적 작용

Epidermal growth factor (EGF) blocks gastric acid and pepsin secretion and increases gastrointestinal cell proliferation. EGF stimulates proliferation and migration in bone marrow stromal cells (BMSC), that gives rise to osteoblasts, chondrocytes and adipocytes. It functions as a strong mitogenic factor for various cultured cells. Mutations in this gene is linked to hypomagnesemia. EGF plays a major role in the maintenance of hair and skin development.

물리적 형태

Lyophilized from 0.2 μm filtered solution in ammonium acetate buffer.

제조 메모

Purified by gel filtration and ion-exchange chromatography.

분석 메모

The biological activity is measured in a proliferation assay using BALB/MK cells.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)