D8638

Dodecyltrimethylammonium bromide

≥98%

• 동의어(들): Lauryltrimethylammonium bromide
• Linear Formula: CH₃(CH₂)₁₁N(CH₃)₃Br
• CAS Number: 1119-94-4
• Molecular Weight: 308.34
• Beilstein: 3597463
• EC Number: 214-290-3
• MDL number: MFCD00011767
• UNSPSC 코드: 12161900
• PubChem Substance ID: 24894108
• NACRES: NA.25

속성

• 생물학적 소스: synthetic (oragnic)
• Quality Level: 200
• 설명: cationic
• 분석: ≥98%
• 형태: powder
• 분자량: 308.34 g/mol
• mp: 246 °C (dec.) (lit.)
• solubility: 954 g/L at 20 °C
• density: 1.17 g/cm³ at 20 °C (68 °F)
• SMILES string: [Br-].CCCCCCCCCCCC[N+](C)(C)C
• InChI: 1S/C15H34N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16(2,3)4;/h5-15H2,1-4H3;1H/q+1;/p-1
• InChI key: XJWSAJYUBXQQDR-UHFFFAOYSA-M

설명

일반 설명

Dodecyltrimethylammonium bromide (DTAB) is a versatile quaternary ammonium surfactant with a wide range of applications in cell biology and biochemical research. Its unique properties make it a valuable tool for solubilizing proteins and peptides, extracting DNA, and lysing cells. In proteomics research, DTAB plays a crucial role in protein solubilization and purification. Its ability to disrupt hydrophobic interactions and electrostatic forces allows it to effectively solubilize membrane-bound proteins and peptides, making them accessible for analysis and characterization. This property is particularly important in proteomics studies involving membrane proteins, which are often difficult to solubilize using conventional methods.

Beyond protein solubilization, this cationic detergent also finds application in DNA extraction procedures. Its ability to interact with DNA and alter its conformation facilitates the release of DNA from cellular components, enabling its subsequent purification and analysis. This property is particularly useful in the isolation of DNA from various biological samples, including tissues, cells, and microorganisms. Furthermore, DTAB demonstrates effectiveness in cell lysis processes. Its ability to disrupt cell membranes and release intracellular components makes it a valuable tool for breaking down cells and accessing their contents. This property has applications in various biological studies, including protein extraction, enzyme assays, and cellular component analysis.

Dodecyltrimethylammonium bromide (DTAB) stands as a versatile and widely applicable surfactant with a diverse range of applications in proteomics research, cell biology, and biochemical research. Its ability to solubilize proteins and peptides, extract DNA, and lyse cells makes it an essential tool for various biological studies and analytical techniques.

애플리케이션

Dodecyltrimethylammonium bromide has been used in a study to assess the distribution of binary mixed counterions in surfactant adsorbed films. It has also been used in a study to investigate chain length compatibility of surfactants for extraction of organophosphorous pesticides.

Dodecyltrimethylammonium bromide has been used to lyse neonatal normal human epidermal keratinocyte (NHEK) cells for the quantification of intracellular nicotinamide adenine dinucleotide phosphate (NADP⁺) and NADPH (reduced form) content.

특징 및 장점

High-quality compound for your cell biology and biochemical research

기타 정보

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안전성 정보

• 픽토그램: GHS06,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H301,H315,H319,H410
• 예방조치 성명서: P264 - P270 - P273 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves