D7571
Dimaprit dihydrochloride
≥98% (NMR)
동의어(들):
Carbamimidothioic acid, 3-(dimethylamino)propyl ester, hydrochloride (1:2), Dimaprit-2HCl
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
실험식(Hill 표기법):
C6H15N3S · 2HCl
CAS Number:
Molecular Weight:
234.19
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77
추천 제품
분석
≥98% (NMR)
형태
powder
색상
white to off-white
solubility
H2O: ≥50 mg/mL
주관자
Roche
저장 온도
−20°C
SMILES string
Cl.Cl.CN(C)CCCSC(N)=N
InChI
1S/C6H15N3S.2ClH/c1-9(2)4-3-5-10-6(7)8;;/h3-5H2,1-2H3,(H3,7,8);2*1H
InChI key
DFWCPLGXFMSUCW-UHFFFAOYSA-N
생화학적/생리학적 작용
The histamine H2 receptor influences various cardiovascular responses, including vasodilation and cardiac rhythm, regulates gastric acid secretion, and also plays a role in the immune system by inhibiting antibody production, T cell proliferation and cytokine production. Histamine receptors are members of the GPCR family, and H2 mediates cell signaling via internalization and interaction with the GTPase dynamin.
특징 및 장점
This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Tetsuya Tachibana et al.
Domestic animal endocrinology, 66, 57-63 (2018-11-26)
Infectious conditions are associated with reduced food passage through the digestive tract in both mammals and chicks; however, the precise mechanism mediating this response in chicks remains unclear. The purpose of the present study was to determine if mast cells
Hamid Ghasemi et al.
Pharmacological reports : PR, 69(6), 1393-1401 (2017-11-18)
Histamine and opiate systems contribute to supraspinal processing of pain. In the present study, we investigated the effects of microinjection of histamine and agonists and antagonists of histamine H The thalamic ventral posterolateral nuclei were bilaterally implanted with two guide
Xiaowei Chen et al.
Cell stem cell, 21(6), 747-760 (2017-12-05)
Myeloid-biased hematopoietic stem cells (MB-HSCs) play critical roles in recovery from injury, but little is known about how they are regulated within the bone marrow niche. Here we describe an auto-/paracrine physiologic circuit that controls quiescence of MB-HSCs and hematopoietic progenitors
J Kitanaka et al.
Neuroscience, 147(3), 765-777 (2007-06-16)
The administration of methamphetamine (METH, 10 mg/kg, i.p.) to male ICR mice induced stereotyped behavior consisting of nail and/or wood chip biting (86.0%), continuous sniffing (12.0%), head bobbing (1.1%), and circling (1.0%) during the observation period of 1 h. Pretreatment
J Sethi et al.
Neuroscience, 217, 84-95 (2012-05-15)
Histamine acts centrally to increase energy expenditure and reduce body weight by mechanisms not fully understood. It has been suggested that in the obese state hypothalamic histamine signaling is altered. Previous studies have also shown that histamine acting in the
문서
We offers many products related to histamine receptors for your research needs.
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