추천 제품
Quality Level
분석
≥98% (HPLC)
양식
powder
저장 조건
desiccated
protect from light
색상
white
저장 온도
−20°C
SMILES string
O.N[C@H](C(O)=O)c1cc(O)cc(O)c1
InChI
1S/C8H9NO4.H2O/c9-7(8(12)13)4-1-5(10)3-6(11)2-4;/h1-3,7,10-11H,9H2,(H,12,13);1H2/t7-;/m0./s1
InChI key
QZEFIWWBQUKNFA-FJXQXJEOSA-N
유전자 정보
human ... GRM1(2911)
애플리케이션
(S)-3,5-Dihydroxyphenylglycine hydrate has been used:
- as mGluR1/5 agonist for metabotropic glutamate receptor 1 (mGluR1/5) activation in synaptoneurosomal preparations
- in ACSF for DHPG stimulation
- to inject into basolateral amygdala to study its effect on memory expression
생화학적/생리학적 작용
(S)-3,5-Dihydroxyphenylglycine hydrate is a group I metabotropic glutamate receptor agonist.
특징 및 장점
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
주의사항
air sensitive
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
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Biochimica et Biophysica Acta - Molecular Cell Research, 1864(6), 1071-1087 (2017)
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Fragile X syndrome is caused by FMR1 gene silencing and loss of the encoded fragile X mental retardation protein (FMRP), which binds to mRNA and regulates translation. Studies in the Fmr1-/y mouse model of fragile X syndrome indicate that aberrant
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The hypothalamic paraventricular nucleus (PVN) plays a major role in generating increased sympathetic output in hypertension. Although group III metabotropic glutamate receptors (mGluRs) are expressed in the hypothalamus, little is known about their contribution to regulating PVN presympathetic neurons in
관련 콘텐츠
DISCOVER Bioactive Small Molecules for Neuroscience
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