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Merck
모든 사진(1)

Key Documents

C8284

Sigma-Aldrich

Anti-C-Reactive Protein antibody produced in goat

whole antiserum

동의어(들):

Anti-CRP

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

goat

결합

unconjugated

항체 형태

whole antiserum

항체 생산 유형

primary antibodies

클론

polyclonal

포함

15 mM sodium azide

종 반응성

human

기술

Ouchterlony double diffusion: 1:16-1:32

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... CRP(1401)

일반 설명

C-reactive protein (CRP) is a first acute-phase plasma protein. It is synthesized in the hepatocyte and the concentration increase during inflammatory states even chronic inflammation. It′s level can increase during inflammation by up to 100 or 500 times.
C-reactive protein is encoded by the gene mapped to human chromosome 1q23.2.

특이성

Specificity for human CRP is determined by immunoelectrophoresis (IEP) versus human CRP positive serum and purified human CRP. No reactivity with normal human serum is observed.

애플리케이션

Anti-C-Reactive Protein antibody produced in goat has been used in enzyme-linked immunosorbent assay (ELISA). It has also been used in immunoassay reproducibility and binding affinity investigation of CRP-anti-CRP interaction.
Anti-C-Reactive protein antibody has been used in:
  • immunoassay reproducibility and binding affinity investigation of CRP-anti-CRP interaction.
  • in-house ELISA assay to study the CRP levels in plasma sample.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Enzyme-linked immunosorbent assay (1 paper)

생화학적/생리학적 작용

C-reactive protein (CRP) plays an important role to provide an enhanced clearance of inappropriate materials from the plasma, whether these are of extrinsic origin, such as microorganisms and their products or the autologous products of cell damage and death. It acts as a systemic biomarker of acute inflammation and tissue damage.

물리적 형태

Goat Anti-Human CRP is supplied as a liquid containing 0.1% sodium azide (see MSDS) as preservative.

저장 및 안정성

For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Yu-Jui Fan et al.
Langmuir : the ACS journal of surfaces and colloids, 26(17), 13751-13754 (2010-08-03)
A new technique is developed to measure the nanoparticles' brownian motions by employing microparticle-tracking velocimetry (micro-PTV) in evanescent wave field, which can provide high signal-to-noise ratio images for analyzing nanoparticles' movements. This method enables real-time detection of C-reactive proteins (CRPs)
Intestinal parasites coinfection does not alter plasma cytokines profile elicited in acute malaria in subjects from endemic area of Brazil
Sanchez-AJC, et al.
Mediators of Inflammation (2014)
J Hurlimann et al.
The Journal of experimental medicine, 123(2), 365-378 (1966-02-01)
The site of formation of C-reactive protein (CxRP, CRP) has been studied with tissues from rabbits, monkeys, and human beings. Rabbits and monkeys were stimulated to produce the acute phase protein by injection of turpentine, croton oil, endotoxin, paratyphoid-typhoid vaccine
Josué da Costa Lima-Junior et al.
Memorias do Instituto Oswaldo Cruz, 107(8), 1035-1041 (2013-01-09)
The haematological changes and release of soluble mediators, particularly C-reactive protein (CRP) and nitric oxide (NO), during uncomplicated malaria have not been well studied, especially in Brazilian areas in which the disease is endemic. Therefore, the present study examined these
M B Pepys et al.
Advances in immunology, 34, 141-212 (1983-01-01)
The acute phase response among plasma proteins is a normal response to tissue injury and is therefore a fundamental aspect of many diverse disease processes. It probably usually has a beneficial net function in limiting damage and promoting repair but

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