C6013
Cholesteryl hemisuccinate tris salt
anionic detergent
동의어(들):
3β-Hydroxy-5-cholestene 3-hemisuccinate, 5-Cholesten-3β-ol 3-hemisuccinate, CHEMS, CHS, Cholesteryl hydrogen succinate
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모든 사진(3)
About This Item
실험식(Hill 표기법):
C31H50O4 · C4H11NO3
CAS Number:
Molecular Weight:
607.86
MDL number:
UNSPSC 코드:
12352211
eCl@ss:
39023139
PubChem Substance ID:
NACRES:
NA.77
추천 제품
생물학적 소스
synthetic (organic)
Quality Level
분석
≥98% (TLC)
양식
powder
작용기
ester
배송 상태
ambient
저장 온도
−20°C
SMILES string
NC(CO)(CO)CO.CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OC(=O)CCC(O)=O
InChI
1S/C31H50O4.C4H11NO3/c1-20(2)7-6-8-21(3)25-11-12-26-24-10-9-22-19-23(35-29(34)14-13-28(32)33)15-17-30(22,4)27(24)16-18-31(25,26)5;5-4(1-6,2-7)3-8/h9,20-21,23-27H,6-8,10-19H2,1-5H3,(H,32,33);6-8H,1-3,5H2/t21-,23+,24+,25-,26+,27+,30+,31-;/m1./s1
InChI key
SLDYONDUXRBLLR-XTCKSVDZSA-N
애플리케이션
Cholesteryl hemisuccinate tris salt has been used:
- to prepare solubilization buffer for glucan synthase assay
- to prepare immunoprecipitation buffer for immobilization of opioid receptors on paramagnetic beads.
- as a membrane stabilizer for liposomes and protein synaptogyrin-1
- as a component of a folate-modified self-microemulsifying drug delivery system.
- with N-dodecyl β-D-maltoside (DDM) to solubilize erythrocyte ghosts and chemokine receptor CCR1
- for protein solubilization
생화학적/생리학적 작용
Cholesteryl hemisuccinate is an ionizable anionic detergent that stabilizes large unilamellar vesicles. These liposome vesicles act as delivery agents for anticancer drugs, oligonucleotides and antibiotics. Cholesteryl succinate also reportedly exhibits antiproliferative activity and may be clinically useful as antitumor agent.
제조 메모
Cholesteryl hemisuccinate tris salt yields clear, colorless solution in methanol at 10 mg/ml.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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