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Merck
모든 사진(1)

Key Documents

C3230

Sigma-Aldrich

Coelenterazine h

solid

동의어(들):

2-Deoxycoelenterazine, CLZN-h

로그인조직 및 계약 가격 보기


About This Item

실험식(Hill 표기법):
C26H21N3O2
CAS Number:
Molecular Weight:
407.46
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.32

형태

solid

Quality Level

저장 온도

−20°C

SMILES string

Oc1ccc(cc1)C2=CN3C(=O)C(Cc4ccccc4)=NC3=C(Cc5ccccc5)N2

InChI

1S/C26H21N3O2/c30-21-13-11-20(12-14-21)24-17-29-25(22(27-24)15-18-7-3-1-4-8-18)28-23(26(29)31)16-19-9-5-2-6-10-19/h1-14,17,27,30H,15-16H2

InChI key

KAEGGIFPLJZUOZ-UHFFFAOYSA-N

일반 설명

Coelenterazine is an imidazopyrazinone derivative. It is a substrate for bioluminescence in many luminous marine organisms.

생화학적/생리학적 작용

10 times higher luminescence intensity than native coelenterazine.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

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Markova S V and Vysotski E S
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Nature neuroscience, 13(4), 513-520 (2010-03-23)
Existing techniques for monitoring neural activity in awake, freely behaving vertebrates are invasive and difficult to target to genetically identified neurons. We used bioluminescence to non-invasively monitor the activity of genetically specified neurons in freely behaving zebrafish. Transgenic fish with
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Mitogen-activated protein kinases (MAPKs) control essential eukaryotic signaling pathways. While much has been learned about MAPK activation, much less is known about substrate recruitment and specificity. MAPK substrates may be other kinases that are crucial to promote a further diversification

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