모든 사진(1)
About This Item
실험식(Hill 표기법):
C8H16ClNO2 · HCl
CAS Number:
Molecular Weight:
230.13
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77
추천 제품
Quality Level
분석
>97% (GC)
형태
powder
저장 조건
desiccated
색상
white
mp
78-81 °C
solubility
H2O: >5 mg/mL
ethanol: soluble
methanol: soluble
저장 온도
−20°C
SMILES string
Cl[H].CCN(CCCl)CCOC(C)=O
InChI
1S/C8H16ClNO2.ClH/c1-3-10(5-4-9)6-7-12-8(2)11;/h3-7H2,1-2H3;1H
InChI key
CHWPASAPXMNLKO-UHFFFAOYSA-N
애플리케이션
Acetylethylcholine mustard hydrochloride has been used as a precursor in ethylcholine aziridinium (AF64A) preparation. It has also been used in the pharmacokinetic study to investigate its role in neuromuscular junction (NMJ) signal transmission and function.
생화학적/생리학적 작용
Acetylethylcholine mustard hydrochloride can reduce the contraction frequency of the myotubes by inhibiting the synthesis of acetylethylcholine (Ach) with the half-maximal inhibitory concentration (IC50) of 1.22 mM.
Acetylethylcholine mustard is a precursor for ethylcholine mustard aziridinium ion (AF-64A); irreversible ligand for the high affinity choline transport system; specific presynaptic long action cholinotoxin; inhibitor of choline acetyl-transferase.
주의사항
Extremely hygroscopic.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 1 - STOT SE 3
표적 기관
Nervous system, Respiratory system
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point (°F)
204.8 °F - closed cup
Flash Point (°C)
96 °C - closed cup
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Pennapa Chonpathompikunlert et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48(3), 798-802 (2009-12-26)
Recently, numerous medicinal plants possessing profound central nervous system effects and antioxidant activity have received much attention as food supplement to improve cognitive function against cognitive deficit condition including in Alzheimer's disease condition. Based on this information, the effect of
Surapon N Charoensook et al.
Integrative biology : quantitative biosciences from nano to macro, 9(12), 956-967 (2017-11-24)
In vitro models of the neuromuscular junction (NMJ) are emerging as a valuable tool to study synaptogenesis, synaptic maintenance, and pathogenesis of neurodegenerative diseases. Many models have previously been developed using a variety of cell sources for skeletal muscle and
Yvonne L Dorland et al.
Scientific reports, 9(1), 14401-14401 (2019-10-09)
Culture expanded mesenchymal stromal cells (MSCs) are being extensively studied for therapeutic applications, including treatment of graft-versus-host disease, osteogenesis imperfecta and for enhancing engraftment of hematopoietic stem cells after transplantation. Thus far, clinical trials have shown that the therapeutic efficiency
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