모든 사진(1)
About This Item
실험식(Hill 표기법):
C8H16ClNO2 · HCl
CAS Number:
Molecular Weight:
230.13
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77
추천 제품
분석
>97% (GC)
양식
powder
저장 조건
desiccated
색상
white
mp
78-81 °C
solubility
H2O: >5 mg/mL
ethanol: soluble
methanol: soluble
저장 온도
−20°C
SMILES string
Cl[H].CCN(CCCl)CCOC(C)=O
InChI
1S/C8H16ClNO2.ClH/c1-3-10(5-4-9)6-7-12-8(2)11;/h3-7H2,1-2H3;1H
InChI key
CHWPASAPXMNLKO-UHFFFAOYSA-N
애플리케이션
Acetylethylcholine mustard hydrochloride has been used as a precursor in ethylcholine aziridinium (AF64A) preparation. It has also been used in the pharmacokinetic study to investigate its role in neuromuscular junction (NMJ) signal transmission and function.
생화학적/생리학적 작용
Acetylethylcholine mustard hydrochloride can reduce the contraction frequency of the myotubes by inhibiting the synthesis of acetylethylcholine (Ach) with the half-maximal inhibitory concentration (IC50) of 1.22 mM.
Acetylethylcholine mustard is a precursor for ethylcholine mustard aziridinium ion (AF-64A); irreversible ligand for the high affinity choline transport system; specific presynaptic long action cholinotoxin; inhibitor of choline acetyl-transferase.
Acetylethylcholine mustard is an irreversible ligand for the high affinity choline transport system; specific presynaptic long action cholinotoxin; inhibitor of choline acetyl-transferase.
주의사항
Extremely hygroscopic.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 1 - STOT SE 3
표적 기관
Nervous system, Respiratory system
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point (°F)
204.8 °F - closed cup
Flash Point (°C)
96 °C - closed cup
Pennapa Chonpathompikunlert et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48(3), 798-802 (2009-12-26)
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Scientific reports, 9(1), 14401-14401 (2019-10-09)
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