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Merck
모든 사진(1)

Key Documents

B9003

Sigma-Aldrich

Boc-Glu-OBzl

≥98% (TLC)

동의어(들):

Boc-L-glutamic acid 1-benzyl ester

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About This Item

실험식(Hill 표기법):
C17H23NO6
CAS Number:
Molecular Weight:
337.37
Beilstein:
2482076
MDL number:
UNSPSC 코드:
12352209
PubChem Substance ID:
NACRES:
NA.26

product name

Boc-Glu-OBzl,

분석

≥98% (TLC)

형태

powder

색상

white to off-white

mp

95-99 °C

응용 분야

peptide synthesis

저장 온도

−20°C

SMILES string

CC(C)(C)OC(=O)N[C@@H](CCC(O)=O)C(=O)OCc1ccccc1

InChI

1S/C17H23NO6/c1-17(2,3)24-16(22)18-13(9-10-14(19)20)15(21)23-11-12-7-5-4-6-8-12/h4-8,13H,9-11H2,1-3H3,(H,18,22)(H,19,20)/t13-/m0/s1

InChI key

CVZUKWBYQQYBTF-ZDUSSCGKSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

생화학적/생리학적 작용

Boc-Glu-OBzl is an N-terminal protected amino acid used in solid-phase peptide synthesis (SPPS) to make unique peptides containing glutamate benzyl ester residues.

기질

Substrate for Vitamin K-dependent carboxylation.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

이미 열람한 고객

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K H Hsieh et al.
International journal of peptide and protein research, 48(3), 292-298 (1996-09-01)
Side reactions in peptide synthesis indicate steps needing improvement as well as opportunities for structural diversification in combinatorial design. Among the side reactions observed in this study, transesterification of Boc-Glu(OBzl) occurred in TMAH-catalyzed resin attachment, leading to Boc-DKKREE(OMe) in solid-phase
E I Lepist et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 11(1), 43-50 (2000-07-29)
One approach to increase drug stability and to facilitate oral absorption of low bioavailability drugs may be to design oligopeptide ester prodrugs which are stable in the gastrointestinal tract, are transported via the oligopeptide transporter, and finally release the parent
Robert G Boyle et al.
Journal of peptide science : an official publication of the European Peptide Society, 11(3), 161-165 (2005-01-07)
An investigation of a series of single replacement analogues of PrRP-(19-31)-peptide has shown that good functional activity was retained when Phe31 was replaced with His(Bzl), Phe(4Cl), Nle, Trp, Cys(Bzl) or Glu(OBzl); when Val28 or Ile25 was replaced with Phg; when
S Romiti et al.
Journal of biochemical and biophysical methods, 11(1), 59-68 (1985-05-01)
Methods are presented that describe alternative protocols for the isolation of rat liver microsomes containing the vitamin K-dependent carboxylase and the procedure in which the solubilized enzyme is assayed. The method for determining the rate of 14CO2 incorporation into low

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