B4153
Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride
~95%
동의어(들):
Boc-Gln-Ala-Arg-AMC hydrochloride, Boc-Gln-Ala-Arg-Mca hydrochloride
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
실험식(Hill 표기법):
C29H42N8O8 · HCl
CAS Number:
Molecular Weight:
667.15
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:
NACRES:
NA.32
추천 제품
분석
~95%
형태
powder
solubility
methanol: 50 mg/mL, clear, colorless
저장 온도
−20°C
SMILES string
CC(NC(=O)C(CCC(N)=O)NC(=O)OC(C)(C)C)C(=O)NC(CCCNC(N)=N)C(=O)Nc1ccc2C(C)=CC(=O)Oc2c1
InChI
1S/C29H42N8O8/c1-15-13-23(39)44-21-14-17(8-9-18(15)21)35-26(42)19(7-6-12-33-27(31)32)36-24(40)16(2)34-25(41)20(10-11-22(30)38)37-28(43)45-29(3,4)5/h8-9,13-14,16,19-20H,6-7,10-12H2,1-5H3,(H2,30,38)(H,34,41)(H,35,42)(H,36,40)(H,37,43)(H4,31,32,33)
InChI key
LQSLBVXESNRILG-UHFFFAOYSA-N
일반 설명
Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride is a fluorogenic and cell-permeable trypsin substrate.
애플리케이션
Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride has been used as a fluorogenic substrate to measure the enzymatic activity of trypsin.
포장
Bottomless glass bottle. Contents are inside inserted fused cone.
기질
Substrate for trypsin
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Dodheri Syed Samiulla et al.
Organic and medicinal chemistry letters, 2(1), 27-27 (2012-07-17)
Caspase-3 inhibition has been demonstrated to be therapeutically effective in moderating excessive programmed cell death. Interest in caspase-3 as a therapeutic target has led many to pursue the development of inhibitors. To date, only a few series of non-peptide inhibitors
Sudarshan R Malla et al.
Cellular and molecular life sciences : CMLS, 77(9), 1811-1825 (2019-08-01)
Premature intrapancreatic trypsinogen activation is widely regarded as an initiating event for acute pancreatitis. Previous studies have alternatively implicated secretory vesicles, endosomes, lysosomes, or autophagosomes/autophagolysosomes as the primary site of trypsinogen activation, from which a cell-damaging proteolytic cascade originates. To
José Manuel Mazón-Suástegui et al.
Homeopathy : the journal of the Faculty of Homeopathy, 109(1), 3-13 (2019-08-28)
This research aimed to observe the effect of homeopathically prepared Vibrio parahaemolyticus (ViP) and V. alginolyticus (ViA) and the commercial homeopathic compound Similia (Phosphoricum acidum and Silicea terra) on the digestive enzyme activities of Seriola rivoliana juveniles under usual culture
S Kawabata et al.
European journal of biochemistry, 172(1), 17-25 (1988-02-15)
Seventy-four peptide amides of 7-amino-4-methylcoumarin (Mec) of the type Boc-Xaa-Yaa-Arg-NH-Mec were newly synthesized and tested to find specific substrates for blood-clotting proteases and trypsin. The Xaa and Yaa residues of these substrates have been replaced by 12 and 15 different
Carmen Navarro-Guillén et al.
PloS one, 16(4), e0248356-e0248356 (2021-04-10)
New and more efficient methods to sustainably intensify Aquaculture production are essential to attain the seafood demand for direct human consumption in the near future. Nutrition has been identified as one strategy of early exposure that might affect animal early
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