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Merck
모든 사진(1)

주요 문서

B3503

Sigma-Aldrich

Benzidine

≥98.0% (N)

동의어(들):

4,4′-Diaminobiphenyl

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About This Item

실험식(Hill 표기법):
C12H12N2
CAS Number:
Molecular Weight:
184.24
Beilstein:
742770
EC Number:
MDL number:
UNSPSC 코드:
12352116
PubChem Substance ID:
NACRES:
NA.25

Quality Level

분석

≥98.0% (N)

양식

powder

SMILES string

Nc1ccc(cc1)-c2ccc(N)cc2

InChI

1S/C12H12N2/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10/h1-8H,13-14H2

InChI key

HFACYLZERDEVSX-UHFFFAOYSA-N

유전자 정보

human ... UGT1A4(54657)

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Benzidine (4,4′-Diaminobiphenyl) is an environmental genotoxin that posses increased risks of cancer to exposed people. Benzidine may be used as a reference material in procedures that analyze for benzidine. Benzidine can be used in studies on its mechanisms of genotoxicity.

생화학적/생리학적 작용

Initiates tumors in the bladder under experimental conditions.

픽토그램

Health hazardExclamation markEnvironment

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Benzidine: a bladder carcinogen.
R G Wendel et al.
The Journal of urology, 111(5), 607-610 (1974-05-01)
Brian J Pak et al.
PLoS neglected tropical diseases, 8(8), e3002-e3002 (2014-08-08)
Strongyloidiasis is a persistent human parasitic infection caused by the intestinal nematode, Strongyloides stercoralis. The parasite has a world-wide distribution, particularly in tropical and subtropical regions with poor sanitary conditions. Since individuals with strongyloidiasis are typically asymptomatic, the infection can
G Choudhary
Chemosphere, 32(2), 267-291 (1996-01-01)
Benzidine, an odorless, white to slightly reddish-white crystalline organic compound, is an environmental contaminant that has been identified at about 30 National Priorities List (NPL) hazardous waste sites in the United States. In the environment, it is usually found attached
P D Josephy
Federation proceedings, 45(10), 2465-2470 (1986-09-01)
Benzidine oxidative activation may proceed by peroxidase-catalyzed one-electron oxidation via free radical intermediates, or by N-acetylation followed by monooxygenase-catalyzed N-hydroxylation. The peroxidase route has been examined by using horseradish peroxidase or prostaglandin H synthase in vitro. In the presence of
J Whysner et al.
Pharmacology & therapeutics, 71(1-2), 107-126 (1996-01-01)
The aromatic amine benzidine (BZ) has produced various tumors, including liver tumors, in mice, rats and hamsters. BZ forms DNA adducts in rodent liver, and it is positive in most genotoxicity tests. Only bladder tumors are produced in dogs and

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