A9605

AC-93253 iodide

≥98% (HPLC)

• 동의어(들): 2-[3-(1,3-Dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propenyl]-3-ethyl-benzothiazolium iodide
• 실험식(Hill 표기법): C₂₃H₂₅N₂SI
• CAS Number: 108527-83-9
• Molecular Weight: 488.43
• MDL number: MFCD03769029
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24724406
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 양식: solid
• 저장 조건: desiccated
• 색상: dark purple
• solubility: DMSO: >10 mg/mL; H₂O: insoluble
• 저장 온도: 2-8°C
• SMILES string: [I-].CC[n+]1c(\C=C\C=C2\N(C)c3ccccc3C2(C)C)sc4ccccc14
• InChI: 1S/C23H25N2S.HI/c1-5-25-19-13-8-9-14-20(19)26-22(25)16-10-15-21-23(2,3)17-11-6-7-12-18(17)24(21)4;/h6-16H,5H2,1-4H3;1H/q+1;/p-1
• InChI key: TWBRXRGFFUATNI-UHFFFAOYSA-M

설명

생화학적/생리학적 작용

AC-93253 is a potent, cell permeable, subtype selective RAR (RARα) agonist. EC₅₀ = 6.3 μM. AC-93253 has high selectivity; 89% for RARα vs 67% for RARβ1, 35% for RARβ2, and 11% for RARγ.

Potent, cell permeable, subtype selective RAR (RARα) agonist.

특징 및 장점

This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable