A9434

Ammonium chloride

for molecular biology, suitable for cell culture, ≥99.5%

• 동의어(들): Salmiac
• Linear Formula: NH₄Cl
• CAS Number: 12125-02-9
• Molecular Weight: 53.49
• Beilstein: 4371014
• EC Number: 235-186-4
• MDL number: MFCD00011420
• UNSPSC 코드: 12352302
• eCl@ss: 38050207
• PubChem Substance ID: 24891452
• NACRES: NA.31

속성

• Grade: for molecular biology
• vapor density: 1.9 (vs air)
• vapor pressure: 1 mmHg ( 160.4 °C)
• 분석: ≥99.5%
• 형태: powder or crystals
• 기술: cell culture | mammalian: suitable
• mp: 340 °C (subl.) (lit.)
• 음이온 미량물: phosphate (PO₄^3-): ≤2 ppm; sulfate (SO₄^2-): ≤20 ppm
• 양이온 미량물: Fe: ≤2 ppm; heavy metals (as Pb): ≤5 ppm
• 외래 활성: DNase, RNase, protease, none detected
• SMILES string: N.Cl
• InChI: 1S/ClH.H3N/h1H;1H3
• InChI key: NLXLAEXVIDQMFP-UHFFFAOYSA-N

설명

애플리케이션

Ammonium chloride has been used:

• as an inhibitor of endosome acidification in vero cells
• as an autophagy inhibitor in vascular smooth muscle cell (VSMC)
• in the depletion and lysis of erythrocytes in testis parenchyma homogenate

생화학적/생리학적 작용

Ammonium chloride is one of the three principal components of the nitrogen cycle. Ammonium chloride administration promotes creatinine and urea clearance andinduces metabolic acidosis in mice. Excess of ammonium chloride inhibits Kreb′s pathway in brain and depletes ATP in astrocytes. Ammonium chloride inhibits acidification in the endosome-lysosome system. Ammonium chloride is a hemolysing agent used for the lysis of erythrocytes.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H319
• 예방조치 성명서: P264 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves