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Merck
모든 사진(1)

문서

A5845

Sigma-Aldrich

N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin

≥95% (HPLC), powder

동의어(들):

Ac-LEHD-AFC

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C33H38O11N7F3
Molecular Weight:
765.69
MDL number:
MFCD01862610
UNSPSC 코드:
12352209
PubChem Substance ID:
329770876
NACRES:
NA.32

Quality Level

200

분석

≥95% (HPLC)

형태

powder

색상

white

solubility

DMSO/DMF: 20 mM

저장 온도

−20°C

SMILES string

CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(O)=O)C(=O)Nc2ccc3c(OC(=O)C=C3C(F)(F)F)c2

InChI

1S/C33H38F3N7O11/c1-15(2)8-22(39-16(3)44)31(52)41-21(6-7-26(45)46)29(50)42-23(9-18-13-37-14-38-18)32(53)43-24(12-27(47)48)30(51)40-17-4-5-19-20(33(34,35)36)11-28(49)54-25(19)10-17/h4-5,10-11,13-15,21-24H,6-9,12H2,1-3H3,(H,37,38)(H,39,44)(H,40,51)(H,41,52)(H,42,50)(H,43,53)(H,45,46)(H,47,48)/t21-,22-,23-,24-/m0/s1

InChI key

HULKIXRFKRCRHD-ZJZGAYNASA-N

유전자 정보

human ... CARD9(64170) , CASP9(842)
mouse ... CARD9(332579) , CASP9(12371)
rat ... CARD9(64171) , CASP9(58918)

Amino Acid Sequence

NAc-Leu-Glu-His-Asp-AFC

일반 설명

Amino acid derivatives of 7-amido-4-trifluoromethylcoumarin (AFC) are blue in fluorescence microscopy.

애플리케이션

N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin has been used to assay caspase 9 activity using a substrate-based fluorimetric detection assay

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

시험 성적서(COA)

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