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Merck
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Key Documents

A5043

Sigma-Aldrich

Adenosine Deaminase from bovine spleen

Type X, buffered aqueous glycerol solution, ≥130 units/mg protein

동의어(들):

ADA, adenosine aminohydrolase, Adenosine aminohydrolase

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About This Item

CAS Number:
효소 위원회 번호:
MDL number:
UNSPSC 코드:
12352204
NACRES:
NA.54

생물학적 소스

bovine spleen

Quality Level

유형

Type X

형태

buffered aqueous glycerol solution

특이 활성도

≥130 units/mg protein

분자량

32.5-33 kDa

양이온 미량물

NH4+: ≤10 μg/mg protein

UniProt 수납 번호

외래 활성

alkaline phosphatase ≤0.01%
guanase ≤0.01%
nucleoside phosphorylase ≤0.1%

저장 온도

2-8°C

유전자 정보

cow ... ADA(280712)

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일반 설명

Molecular weight: 32.5-33 kDa

pI: 4.85

애플리케이션

Adenosine Deaminase from bovine spleen has been used in the immobilization on biostrip for stability and catalytic studies.
Adenosine deaminase is useful in various molecular biology assays, such as glycerol release assays . Adenosine deaminase is a potential target for treatments of combined immunodeficiency disease.

생화학적/생리학적 작용

Adenosine deaminase is a purine catabolic enzyme which catalyzes the deamination of adenosine and 2′-deoxyadenosine with approximately equal specificity. It is ubiquitous in mammalian tissue, and deficiency in adenosine deaminase has been associated with severe combined immunodeficiency disease.

단위 정의

One unit will deaminate 1.0 μmole of adenosine to inosine per min at pH 7.5 at 25 °C.

물리적 형태

Solution in 50% glycerol, 5 mM potassium phosphate, pH 6.0

분석 메모

Protein determined by biuret.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

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