A4475

Anti-Annexin VII antibody, Mouse monoclonal

clone 203-217/6, purified from hybridoma cell culture

• 동의어(들): Synexin
• MDL number: MFCD03792412
• UNSPSC 코드: 12352203
• NACRES: NA.44
• 결합: unconjugated
• application: ARR; ICC; IHC (f); WB
• 클론: 203-217/6, monoclonal
• 종 반응성: mouse, canine, rat, chicken, bovine, human, rabbit
• citations: 5
• 기술: immunocytochemistry: suitable using methanol or 1% paraformaldehyde/0.1% glutaraldehyde; immunohistochemistry (frozen sections): suitable; microarray: suitable; western blot: 0.5-1 μg/mL using whole cell extract of culture mouse connective tissue (A9) cells.

속성

• 생물학적 소스: mouse
• Quality Level: 200
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 203-217/6, monoclonal
• 양식: buffered aqueous solution
• 분자량: antigen 47-51 kDa
• 종 반응성: mouse, canine, rat, chicken, bovine, human, rabbit
• 기술: immunocytochemistry: suitable using methanol or 1% paraformaldehyde/0.1% glutaraldehyde; immunohistochemistry (frozen sections): suitable; microarray: suitable; western blot: 0.5-1 μg/mL using whole cell extract of culture mouse connective tissue (A9) cells.
• 동형: IgG1
• UniProt 수납 번호: P20073
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... ANXA7(310) ; mouse ... Anxa7(11750) ; rat ... Anxa7(155423)

설명

일반 설명

Annexin VII (synexin) is a membrane binding protein that localizes in the nucleus and cytosol. In humans and mice, Annexin VII is encoded by a single gene that has alternatively spliced cassette exons. As a result, two isoforms of molecular mass of 47kDa and 51kDa are expressed. These isoforms differ in their N-terminal region and also have distinct tissue-specific expression patterns.

Anti-Annexin VII antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the 203-217/6 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a recombinant mouse Annexin VII. The human annexin VII (ANXA7) is located on chromosome 10q21.

특이성

Mouse monoclonal anti-annexin VII antibody reacts with human, bovine, rabbit, dog, rat, mouse, and chicken Annexin VII.

면역원

recombinant mouse annexin VII.

애플리케이션

Anti-Annexin VII antibody, Mouse monoclonal has been used in:

• western blotting
• immunocytochemistry
• immunohistochemistry

생화학적/생리학적 작용

Antibodies reacting specifically with Annexin VII serve as an essential tool for the detection of this molecule in various cells. The human annexin VII (ANXA7) possesses a tumor suppressor role in prostate cancer. Hence it can be used an important biomarker along with syndecan-1 to predict the survival rates in prostate cancer patients.

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable