추천 제품
생물학적 소스
mouse
Quality Level
결합
unconjugated
항체 형태
ascites fluid
항체 생산 유형
primary antibodies
클론
XVIF9-G10, monoclonal
분자량
antigen ~110 kDa
종 반응성
human, rat, monkey, sheep, rabbit, guinea pig, canine
농도
1 mg/mL
기술
immunohistochemistry (frozen sections): 3 μg
western blot: 1 μg
동형
IgG1
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... ATP1A3(478)
rat ... Atp1a3(24213)
일반 설명
Mouse monoclonal anti-Na+/K+ ATPase (α3 subunit) antibody reacts specifically with Na+/K+ ATPase α3 subunit. By immunoblotting, the product reacts with human, monkey, sheep, canine, rabbit, guinea pig and rat tissues in which the α3 subunit is expressed. Immunohistochemical staining is consistent with the plasma membrane localization of Na+/K+ ATPase.
Na+/K+ transporting ATPase subunit α1 is an ion transport pump critical for maintaining the gradient of Na and K ions across the plasma membrane.
면역원
canine cardiac microsomes.
애플리케이션
Mouse monoclonal anti-Na+/K+ ATPase (α3 subunit) antibody has been used for chemiluminescent western blot analysis. The product has also been used for co-immunoprecipitation applications.
물리적 형태
Solution in phosphate buffered saline containing 0.05% sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
S Basavappa et al.
Journal of cellular physiology, 174(2), 145-153 (1998-01-15)
The Na+ pump (Na+, K+-ATPase) has been implicated in the regulation of many cellular functions, including cell volume regulation. The effects of inhibiting Na+ pump activity on cell volume and taurine efflux were evaluated in the human neuroblastoma cell line
H Kawai et al.
Journal of neurochemistry, 69(1), 330-339 (1997-07-01)
Three isoforms of catalytic alpha subunits and two isoforms of beta subunits of Na+,K+-ATPase were detected in rat sciatic nerves by western blotting. Unlike the enzyme in brain, sciatic nerve Na+,K+-ATPase was highly resistant to ouabain. The ouabain-resistant alpha1 isoform
Katrina D Linning et al.
Pancreas, 29(3), e64-e76 (2004-09-16)
The limited availability of transplantable human islets has stimulated the development of methods needed to isolate adult pancreatic stem/progenitor cells capable of self-renewal and endocrine differentiation. The objective of this study was to determine whether modulation of intracellular redox state
R Zahler et al.
Circulation research, 78(5), 870-879 (1996-05-01)
The alpha (catalytic) subunit of the Na+ pump (Na+, K(+)-ATPase) has three isoforms; alpha1 is ubiquitous, skeletal muscle expresses predominantly alpha2, and alpha3 has been localized to specific types of neurons and, possibly, to axonal processes. The alpha3 isoform mRNA
Syed J Khundmiri et al.
American journal of physiology. Cell physiology, 291(6), C1247-C1257 (2006-06-30)
Cardiotonic glycosides, like ouabain, inhibit Na(+)-K(+)-ATPase. Recent evidence suggests that low molar concentrations of ouabain alter cell growth. Studies were conducted to examine the effect of ouabain on Akt phosphorylation and rate of cell proliferation in opossum kidney (OK) proximal
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