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Merck
모든 사진(1)

Key Documents

A2536

Sigma-Aldrich

L-2-Aminobutyric acid

BioReagent, suitable for cell culture

동의어(들):

L-α-Aminobutyric acid

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About This Item

실험식(Hill 표기법):
C4H9NO2
CAS Number:
Molecular Weight:
103.12
Beilstein:
1720935
EC Number:
MDL number:
UNSPSC 코드:
12352205
PubChem Substance ID:
NACRES:
NA.75

생물학적 소스

Porcine kidney
microbial
plant

Quality Level

제품 라인

BioReagent

형태

powder

기술

cell culture | mammalian: suitable

solubility

water: 50 mg/mL, clear, colorless

배송 상태

ambient

저장 온도

room temp

SMILES string

CC[C@H](N)C(O)=O

InChI

1S/C4H9NO2/c1-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m0/s1

InChI key

QWCKQJZIFLGMSD-VKHMYHEASA-N

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관련 카테고리

일반 설명

L-2-Aminobutyric acid is synthesized from L-threonine and L-aspartic acid through a ⍺-transamination reaction. It is an L-alanine analogue with an ethyl side chain.

생화학적/생리학적 작용

L-α-Aminobutyric acid (AABA) is an isomer of the non-natural amino acid aminobutyric acid with activity in the γ-glutamyl cycle that regulates glutathione biosynthesis. Recently AABA has been studied as a supplement to in vitro maturation medium (NCSU 23 medium) for culture of oozytes and embryos. This product has been qualified for use in cell culture. AABA is also used as a substitute amino acid for alanine in studies on peptide function.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

l-2-Aminobutyric acid: two fully ordered polymorphs with Z?= 4
Gorbitz CH
Acta Crystallographica Section B, Structural Science, 66(2), 253-259 (2010)
A one-pot system for production of L-2-aminobutyric acid from L-threonine by L-threonine deaminase and a NADH-regeneration system based on L-leucine dehydrogenase and formate dehydrogenase
Tao R, et al.
Biotechnology Letters, 36(4), 835-841 (2014)
Izumi Kawabata et al.
Nature communications, 3, 722-722 (2012-03-08)
Synaptic remodelling coordinated with dendritic growth is essential for proper development of neural connections. After establishment of synaptic contacts, synaptic junctions are thought to become stationary and provide fixed anchoring points for further dendritic growth. However, the possibility of active
Cornelia Reimmann et al.
Journal of bacteriology, 186(19), 6367-6373 (2004-09-18)
In Pseudomonas aeruginosa, the antibiotic dihydroaeruginoate (Dha) and the siderophore pyochelin are produced from salicylate and cysteine by a thiotemplate mechanism involving the peptide synthetases PchE and PchF. A thioesterase encoded by the pchC gene was found to be necessary
Kechun Zhang et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(14), 6234-6239 (2010-03-25)
The dramatic increase in healthcare cost has become a significant burden to the world. Many patients are denied the accessibility of medication because of the high price of drugs. Total biosynthesis of chiral drug intermediates is an environmentally friendly approach

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