A1980

A3 hydrochloride

≥98% (HPLC), solid

• 동의어(들): N-(2-Aminoethyl)-5-chloronaphthalene-1-sulfonamide hydrochloride
• 실험식(Hill 표기법): C₁₂H₁₃ClN₂O₂S · HCl
• CAS Number: 78957-85-4
• Molecular Weight: 321.22
• MDL number: MFCD00077311
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24890609
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 형태: solid
• 색상: white
• solubility: DMSO: 24 mg/mL
• 저장 온도: −20°C
• SMILES string: Cl[H].NCCNS(=O)(=O)c1cccc2c(Cl)cccc12
• InChI: 1S/C12H13ClN2O2S.ClH/c13-11-5-1-4-10-9(11)3-2-6-12(10)18(16,17)15-8-7-14;/h1-6,15H,7-8,14H2;1H
• InChI key: VWAGIWCLJAQLAL-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Non-selective casein kinase (CK) inhibitor. A shorter alkyl chain derivative of W-7 that inhibits casein kinase I (K_i = 80 μM), casein kinase II (K_i = 5.1 μM), myosin light chain kinase (K_i = 7.4 μM), protein kinase A (K_i = 4.3 μM), protein kinase C (K_i= 47 μM), and protein kinase G (K_i = 3.8 μM).

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves