A1887

Albumin from human serum

lyophilized powder, essentially fatty acid free

• 동의어(들): HSA
• CAS Number: 70024-90-7
• EC Number: 274-272-6
• MDL number: MFCD00081418
• UNSPSC 코드: 12352202
• eCl@ss: 42010201
• NACRES: NA.25

속성

• 생물학적 소스: human
• Quality Level: 300
• 분석: ≥96% (agarose gel electrophoresis)
• 양식: lyophilized powder
• 분자량: monomer calculated mol wt 66478 Da
• 기술: ELISA: suitable; tissue culture: suitable; western blot: suitable
• 불순물: HIV I and HIVII, HCV and HBsAg, tested negative; ≤0.007% Fatty Acids
• solubility: H₂O: soluble 50 mg/mL, clear to slightly hazy
• UniProt 수납 번호: P02768
• 저장 온도: 2-8°C
• SMILES string: FC(F)(F)C(F)(F)C(F)(F)F
• InChI: 1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
• InChI key: QYSGYZVSCZSLHT-UHFFFAOYSA-N
• 유전자 정보: human ... ALB(213)

설명

일반 설명

Albumin is the most abundant plasma protein in human. It has a molecular weight of 66.5 kDa.

애플리케이션

Albumin from human serum has been used:

• as a carrier of CPT-11 (irinotecan, Campto) and SN-38 to investigate its binding to human plasma proteins
• to study the adsorption of water and acetonitrile (AN) vapor on a human serum albumin
• to study its effect on wound healing process

생화학적/생리학적 작용

Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood.

Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influence their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has widely varied effects on its physiological function.

Serum albumin primarily mediates divalent cation transportation, fatty acid and drug complex formation and transport. The albumin levels in the serum indicate the disease progression in advanced liver disease. Low body weight and decreased serum albumin is associated with colorectal cancer.

제조 메모

Prepared from albumin (A1653)

기타 정보

View more information on human serum albumin.

면책조항

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves