추천 제품
생물학적 소스
yeast
Quality Level
분석
≥98% (HPLC)
양식
powder
solubility
water: 100 mg/mL, clear to very slightly hazy, colorless to very faintly yellow
저장 온도
−20°C
SMILES string
[Na].Nc1ncnc2n(cnc12)C3OC(CO)C(OP(O)(O)=O)C3O
InChI
1S/C10H14N5O7P.Na.H/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(17)7(4(1-16)21-10)22-23(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);;
InChI key
SHIVFKVYHYZMPS-UHFFFAOYSA-N
일반 설명
Adenosine 3′-monophosphate (3′-AMP) is a metabolite produced from the hydrolysis of 2′,3′-cAMP by a family of metal-dependent phosphodiesterases. 3′-AMP inhibits the proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. 2′,3′-cAMP, and 3′-AMP represent a new unexplored pathway for adenosine-based cell regulation.
애플리케이션
Adenosine 3′-monophosphate sodium salt has been used as a marker in thin-layer chromatography (TLC).
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
2′-AMP and 3′-AMP inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors.
Journal of Pharmacology and Experimental Therapeutics, 337, 4440450-4440450 (2011)
Hypertension (Dallas, Tex. : 1979), 56(1), 151-158 (2010-06-03)
Recently we discovered that intact kidneys release into the extracellular compartment 2',3'-cAMP (a positional isomer of 3',5'-cAMP with unknown pharmacology) and metabolize 2',3'-cAMP to 2'-AMP, 3'-AMP, and adenosine. Because adenosine inhibits growth of vascular smooth muscle cells and mesangial cells
Biochemical and biophysical research communications, 398(3), 500-505 (2010-07-06)
The recent report of 2',3'-cAMP isolated from rat kidney is the first proof of its biological existence, which revived interest in this mysterious molecule. 2',3'-cAMP serves as an extracellular adenosine source, but how it is degraded remains unclear. Here, we
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