95200

Vitamin B_12a hydrochloride

≥96% (UV), ≥96% (HPLC)

• 동의어(들): Hydroxocobalamin hydrochloride
• 실험식(Hill 표기법): C₆₂H₈₉CoN₁₃O₁₅P · HCl
• CAS Number: 59461-30-2
• Molecular Weight: 1382.82
• EC Number: 261-772-4
• MDL number: MFCD00167463
• UNSPSC 코드: 12352205
• PubChem Substance ID: 57653658
• NACRES: NA.79

속성

• 생물학적 소스: fermentation/recombinant
• Quality Level: 100
• 분석: ≥96% (HPLC); ≥96% (UV)
• 형태: powder or crystals
• 손실: ≤12% loss on drying, 20 °C (HV)
• 색상: red to dark red
• solubility: methanol: 10 mg/mL at 20 °C, clear, dark red
• 저장 온도: 2-8°C
• SMILES string: Cl.C[C@H](CNC(=O)CC[C@]1(C)[C@@H](CC(N)=O)[C@H]2N([Co+]O)C1=C(C)C3=NC(=CC4=NC(=C(C)C5=N[C@]2(C)[C@@](C)(CC(N)=O)[C@@H]5CCC(N)=O)[C@@](C)(CC(N)=O)[C@@H]4CCC(N)=O)C(C)(C)[C@@H]3CCC(N)=O)OP([O-])(=O)O[C@H]6[C@@H](O)[C@H](O[C@@H]6CO)n7cnc8cc(C)c(C)cc78
• InChI: 1S/C62H90N13O14P.ClH.Co.H2O/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H;;1H2/q;;+3;/p-3/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57+,59-,60+,61+,62+;;;/m1.../s1
• InChI key: KEHNCSYXYMMUCO-BXSGNKEGSA-K

설명

애플리케이션

Vitamin B12a hydrochloride has been used as an antidote for cyanide poisoning.

생화학적/생리학적 작용

Vitamin B12 (cobalamin) refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production and regulation. The physiologically active forms of vitamin B12 include methylcobalamin and adenosylcobalamin, whereas hydroxocobalamin (vitamin B12a, OHCbl) and cyanocobalamin (CNCbl) are storage and delivery forms. Bacteria-derived hydroxocobalamin (OHCbl) and CNCbl are converted in humans to useful coenzyme forms to support metabolic processes such as mitochondrial methylmalonylcoenzyme A mutase conversion of methylmalonic acid (MMA) to succinate to link lipid and carbohydrate metabolism, and activation of methionine synthase, the rate limiting step in the synthesis of methionine.

기타 정보

Review

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)