V6629

Vitamin B₁₂

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥98%

• 동의어(들): α-(5,6-Dimethylbenzimidazolyl)cyanocobamide, CN-Cbl, Cyanocob(III)alamin, Cyanocobalamin
• 실험식(Hill 표기법): C₆₃H₈₈CoN₁₄O₁₄P
• CAS Number: 68-19-9
• Molecular Weight: 1355.37
• Beilstein: 4122889
• EC Number: 200-680-0
• UNSPSC 코드: 12352205
• eCl@ss: 34058004
• PubChem Substance ID: 24900763
• NACRES: NA.75

속성

• 생물학적 소스: synthetic ((organic))
• Quality Level: 200
• 제품 라인: BioReagent
• 분석: ≥98%
• 형태: powder
• 분자량: M_w 1355.37 g/mol
• 기술: cell culture | insect: suitable; cell culture | mammalian: suitable; cell culture | plant: suitable
• 색상: red to brown
• pH: 6
• solubility: water: soluble 50 mg/mL, dark red
• 저장 온도: 2-8°C
• SMILES string: C/C(C1=N[C@]([C@]([C@H](CC(N)=O)[C@@]/2(C)CCC(NC[C@@H](OP([O-])(O[C@H]3[C@@H](O)[C@@H](N4C=[N]5C6=C4C=C(C)C(C)=C6)O[C@@H]3CO)=O)C)=O)([H])N([Co+]5C#N)C2=C(C)/C([C@@H](CCC(N)=O)C/7(C)C)=NC7=C/8)(C)[C@@](C)(CC(N)=O)[C@@H]1CCC(N)=O)=C9N=C8[C@@H](CCC(N)=O)[C@
• InChI: 1S/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;;+2/p-2/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57?,59-,60+,61+,62+;;/m1../s1
• InChI key: RMRCNWBMXRMIRW-QJRSUKKJSA-L

설명

일반 설명

Cyanocobalamin (B12) is a water soluble vitamin, commonly called as cobalamins. Dairy products, meat and eggs are the major sources of this vitamin.

애플리케이션

Vitamin B12 has been used:

• as a component of Erdschreiber′s medium
• as a supplement of Dulbecco′s modified Eagle′s medium used for the isolation of ventricular myocytes from neonatal and adult rats
• orally administered to male quails to study its role in reducing the negative effects of sodium selenite intoxication, in vivo
• as a supplement in DMEM/ medium 199 (M199) medium for differentiation of human myoblasts.

생화학적/생리학적 작용

Vitamin B12 is metabolized to its active form, methylcobalamin. Hindered vitamin B12 uptake is observed in pernicious anemia. Vitamin B12 is essential for erythroblast development. Pregnancy reduces the levels of vitamin B12. Aging reduces vitamin B12 absorption. It works as a coenzyme in fat, carbohydrate and protein metabolism. It is required for growth, genetic stability and survival of cells in vitro. Functions to support one-carbon metabolism. Present in many classical and serum-free formulations.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)