72309

Nicotinic acid

≥99.5% (HPLC)

• 동의어(들): 3-Picolinic acid, Niacin, Pellagra preventive factor, Pyridine-3-carboxylic acid, Vitamin B₃
• 실험식(Hill 표기법): C₆H₅NO₂
• CAS Number: 59-67-6
• Molecular Weight: 123.11
• Beilstein: 109591
• EC Number: 200-441-0
• MDL number: MFCD00006391
• UNSPSC 코드: 12352209
• PubChem Substance ID: 57652411
• NACRES: NA.26

속성

• 생물학적 소스: synthetic
• Quality Level: 200
• 분석: ≥99.5% (HPLC)
• 형태: powder
• 기술: cell culture | mammalian: suitable
• 불순물: ≤0.2% water
• 무기 잔류물: ≤0.05%
• 색상: colorless to white
• mp: 234-238 °C; 236-239 °C (lit.)
• solubility: water: 0.1 g/10 mL, clear, colorless
• density: 1.473 g/cm³ at 25 °C
• SMILES string: OC(=O)c1cccnc1
• InChI: 1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)
• InChI key: PVNIIMVLHYAWGP-UHFFFAOYSA-N
• 유전자 정보: human ... CYP1A2(1544) ; rat ... Chrnb2(54239)

설명

일반 설명

Nicotinic acid, also referred as Niacin or vitamin B₃, is a water soluble vitamin. It is present in vitamin-enriched bread, liver, meat, fish, poultry, potatoes, green vegetables, peanuts and cereals.

애플리케이션

Nicotinic acid has been used as a standard in NAD⁺ precursor rescue experiments. It has also been used as a vitamin supplement in various culture media such as complete medium (CM) and synthetic medium.

생화학적/생리학적 작용

Nicotinic acid or Niacin regulates lipid metabolism by reducing low density lipoprotein (LDL), increasing high-density lipoprotein (HDL) and by inhibiting the progression of atherosclerosis and coronary artery lesions. Niacin deficiency leads to pellagra. In addition to vitamin supplement, niacin is also used as a broad spectrum lipid drug.

기타 정보

Coenzyme and Cofactors, vol 2: Pyridine Nucleotide Coenzymes

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H319
• 예방조치 성명서: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): 379.4 °F - closed cup
• Flash Point (°C): 193 °C - closed cup
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves